Vascular effects of cannabis: Case report and review of literature

Abstract

Marijuana is the 3rd most popular recreational drug and the use of recreational and medical marijuana has been legalized in several states. Knowledge of both acute and chronic adverse effects of cannabis is essential when counseling the public. We report 2 cases who developed arteritis and Raynaud's as a squeal of long term cannabis use and provide a literature review.

Development of Raynaud Phenomenon Following Use of Medical Cannabis

“…Two cases of Raynaud phenomenon developing in relation to cannabis usage were recently reported, both evolving on the order of several months after cannabis initiation. 10 In most cases, cannabis cessation resulted in the halting of disease progression, whereas continued use was associated with disease advancement despite aggressive medical and surgical treatments. 9 Exact pathogenesis remains unclear with few arterial biopsies to rely upon and with their findings varying.…”