Vascular compression of the cochlear nerve and tinnitus: a pathophysiological investigation

Ridder, Dirk De; Vanneste, Sven; Adriaensens, Ine; Lee, Alison Po Kee; Heyning, Paul Van de; Møller, Aage R.

doi:10.1007/s00701-012-1307-3

Cited by 14 publications

(4 citation statements)

References 19 publications

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“…The tinnitus can be perceived unilaterally, bilaterally or holocranially. In bilateral tinnitus it can be perceived as one sound, or it can be perceived as two different sounds in the two ears, all likely to be associated with a different pathophysiology (De Ridder et al, 2007b;De Ridder et al, 2012b) and involving different brain areas (Vanneste et al, 2011a;Vanneste et al, 2011d). There are gender differences in the emotional aspects of tinnitus: in men and women with the same tinnitus intensity, the same tinnitus type and the same amount of distress, there are still differences in mood associated with differences in brain activation .…”

Section: Introductionmentioning

confidence: 99%

An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks

Ridder

Vanneste

Weisz

et al. 2014

Neuroscience & Biobehavioral Reviews

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326

337

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Section: Introductionmentioning

confidence: 99%

An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks

Ridder

Vanneste

Weisz

et al. 2014

Neuroscience & Biobehavioral Reviews

Self Cite

326

337

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“…Microvascular compression of CNVIII has been proposed as a pathophysiological mechanism for tinnitus, with MVD of CNVIII potentially serving as a curative treatment [ 20 , 26 ]. One study showed that patients with both HFS and tinnitus had a neurovascular conflict of both CNVII and CNVIII, while this was less present in HFS patients without tinnitus.…”

Section: Discussionmentioning

confidence: 99%

Tinnitus: an underreported condition following microvascular decompression for hemifacial spasm

Albakri,

Mennink,

Tamasi

et al. 2024

Acta Neurochir

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Purpose While hearing loss is a well-known condition following microvascular decompression (MVD) for hemifacial spasm (HFS), tinnitus is an underreported one. This study aims to identify prevalence, characteristics, severity, and predictors of tinnitus following MVD for HFS. Methods A single-center cohort of 55 HFS patients completed a questionnaire approximately 5 years following MVD. Data encompassed tinnitus presence, side, type, onset, and severity measured by a 10-point Visual Analogue Scale (VAS). Descriptive, correlation, and logistic regression analyses were conducted. Results At surgery, participants’ median age was 58 years (IQR 52–65). The median duration of HFS symptoms before surgery was 5 years (IQR 3–8), slightly predominant on the left (60%). Postoperative tinnitus was reported by 20 patients (36%), versus nine (16%) that reported preoperative tinnitus. Postoperative tinnitus was ipsilateral on the surgical side in 13 patients (65%), bilateral in six (30%), and contralateral in one (5%). Among patients with bilateral postoperative tinnitus, 33% did not have this preoperatively. Tinnitus was continuous in 70% of cases and pulsatile in 30%. Onset of new tinnitus was in 58% immediately or within days, in 25% within three months, and in 17% between three months and one year after surgery. The mean severity of postoperative tinnitus was 5.1 points on the VAS. Preoperative tinnitus and presence of arachnoid adhesions had suggestive associations with postoperative tinnitus in initial analyses (p = 0.005 and p = 0.065). However, preoperative tinnitus was the only significant predictor of postoperative tinnitus (p = 0.011). Conclusion Tinnitus is a common condition following MVD for HFS, with a moderate overall severity. Causes behind postoperative tinnitus remain obscure but could be related to those of postoperative hearing loss in this patient population. Clinicians should be aware of tinnitus following MVD and vigilantly monitor its occurrence, to facilitate prevention efforts and optimize outcome for HFS patients undergoing MVD.

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“…As part of an auditory evaluation, each participant had a pure tone audiometry (PTA); when VP was suspected, auditory-evoked brainstem responses (ABR) were performed. According to Moller's criteria [21,22], compression on the CVN induces a slowing of signal transmission by the respective auditory nerve fibers, and the CVN involvement was suspected as soon as the I-III interpeak latency (IPL) was prolonged more than 2.3 ms on the affected side.…”

Section: Audio-vestibular Assessmentmentioning

confidence: 99%

The “Near”-Narrowed Internal Auditory Canal Syndrome in Adults: Clinical Aspects, Audio-Vestibular Findings, and Radiological Criteria for Diagnosis

Ionescu,

Reynard,

Idriss

et al. 2023

JCM

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Introduction: Vestibular Paroxysmia (VP) refers to short attacks of vertigo, spontaneous or triggered by head movements, and implies the presence of a compressive vascular loop in contact with the cochleovestibular nerve (CVN). Classically, a narrowed internal auditory canal (IAC) corresponds to a diameter of less than 2 mm on CT, usually associated with a hypoplastic CVN on MRI. The aim of this study was to discuss a distinct clinical entity mimicking VP in relation to a “near”-narrowed IAC (NNIAC) and to propose radiological criteria for its diagnosis. Methods: Radiological measurements of the IAC were compared between three groups: the study group (SG, subjects with a clinical presentation suggestive of VP, but whose MRI of the inner ear and pontocerebellar angle excluded a compressive vascular loop) and two control groups (adult and children) with normal vestibular evaluations and no history of vertigo. Results: 59 subjects (18 M and 41 F) were included in the SG. The main symptoms of NNIAC were positional vertigo, exercise- or rapid head movements-induced vertigo, and dizziness. The statistical analysis in the study group showed that the threshold values for diagnosis were 3.3 mm (in tomodensitometry) and 2.9 mm (in MRI) in coronal sections of IAC. Although a significantly lower mean value for axial IAC diameter was found in SG compared with controls, the statistics did not reveal a threshold due to the large inter-individual variations in IAC measurements in normal subjects. There was no significant difference in IAC diameter between the adult and pediatric controls. Conclusions: In the present study, we report a new anatomopathological condition that appears to be responsible for a clinical picture very similar—but not identical—to VP in association with the presence of an NNIAC. The diagnosis requires a careful analysis of the IAC’s shape and diameters in both axial and coronal planes.

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Vascular compression of the cochlear nerve and tinnitus: a pathophysiological investigation

Abstract: Preoperatively, there is a marginal significant difference between the ipsi- and contralateral IPL III-V, which disappears postoperatively.

Cited by 14 publications

References 19 publications

An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks

An integrative model of auditory phantom perception: Tinnitus as a unified percept of interacting separable subnetworks

Tinnitus: an underreported condition following microvascular decompression for hemifacial spasm

The “Near”-Narrowed Internal Auditory Canal Syndrome in Adults: Clinical Aspects, Audio-Vestibular Findings, and Radiological Criteria for Diagnosis

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