Vascular Access

Cesaro, Simone; Minniti, Federica

doi:10.1007/978-3-030-02278-5_22

Cited by 2 publications

(3 citation statements)

References 19 publications

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“…Moreover, some complications might be life-threatening and require the premature removal of the catheter. 3,4 To prevent and identify CVC-related complications early, it is essential to define the correct practices for accessing, maintaining CVC patency, and cleansing CVC exit-site by adopting standard procedures.…”

Section: Introductionmentioning

confidence: 99%

“…The use of CVC is associated with the risk of complications such as malfunctions, infections, and thrombosis that can prolong hospitalization, increase costs, and sometimes determine additional systemic treatments (i.e., antibiotics, antifungals, heparin). Moreover, some complications might be life‐threatening and require the premature removal of the catheter 3,4 …”

Section: Introductionmentioning

confidence: 99%

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Results of a long‐term, prospective study on complications of central venous catheter in pediatric patients with hematologic‐oncologic diseases

Garonzi,

Zeni,

Tridello

et al. 2024

Pediatric Blood & Cancer

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BackgroundCentral venous catheter (CVC)‐related complications remain a significant cause of morbidity in pediatric hematology‐oncology. We prospectively surveyed the incidence of CVC‐related complications in children with hematologic‐oncologic diseases.ProcedureFive‐hundred‐eighty‐one CVCs were inserted in 421 patients from January 2010 to June 2022 (153,731 CVC days observation; follow‐up data up to December 31, 2022).ResultsOverall, 671 complications were recorded (4.365/1000 CVC days): 49.7% malfunctions (1.88/1000 CVC days, 4.8% of CVC early removals), 23.9% bacteremia (0.90/1000, 15.1%), 19.6% mechanical complications (0.74/1000, 70.2%), 20.1% localized infections (0.76/1000, 17.1%), 0.5% thrombosis (0.02/1000, 33.3%). At multivariate analysis, risk factors for malfunction were Broviac–Hickman type of CVC (hazard ratio [HR] 2.5) or Port‐a‐cath (HR 3.4) or Proline (HR 4.3), p < .0001; for bacteremia double‐lumen CVC (HR 3.2, p < .0001); for mechanical complications age at CVC insertion under median (HR 4.5, p < .0001) and Broviac–Hickman (HR 1.6) or Proline (HR 2.7), p = .01; finally for localized infections Broviac–Hickman (HR 2.9) or Proline (HR 4.4), p = .0001. The 2‐year cumulative incidence of premature removal was 23.5%, and risk factors were age at CVC insertion under median (HR 2.4, p < .0001), Broviac–Hickman (HR 2.3) or Proline (HR 4.2), p < .0001.ConclusionsPremature removal occurs in approximately 20%–25% of long‐term CVCs. A surveillance program has a fundamental role in identifying the risk factors for CVC complications and the areas of intervention to improve CVC management.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Results of a long‐term, prospective study on complications of central venous catheter in pediatric patients with hematologic‐oncologic diseases

Garonzi,

Zeni,

Tridello

et al. 2024

Pediatric Blood & Cancer

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“…Such catheters enable, among other things, parenteral drug administration [ 2 ]. Typically, the two types of catheters used for implantation include conventionally inserted central venous catheters (CICCs), inserted through large central veins, and peripherally inserted central catheters (PICCs), implanted through peripheral veins, usually of the upper limb [ 3 ]. CICCs in 1–19% of cases are associated with significant complications during implantation [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Incidence of Catheter-Associated Bloodstream Infections in Stem Cell Recipients—Should We Be “PICCy”?

Milczarek,

Kulig,

Piotrowska

et al. 2024

Cancers

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The management of patients undergoing HSCT requires a multipurpose central venous catheter. Peripheral catheters (PCs), such as peripherally inserted central catheters (PICCs) and MidLine catheters (MLCs), appear to be adequate vascular catheters to be used for stem cell infusion, although their utilization in this indication is not yet common. We analyzed the infectious complications such as blood stream infection (BSI), febrile neutropenia (FN) and central line-associated bloodstream infection (CLBSI) in patients undergoing stem cell infusion through PC and conventionally inserted central catchers (CICCs), and evaluated their impacts on transplantation outcomes. Our results reveal no statistically significant differences between different types of catheter in terms of FN, BSI and CLABSI. Moreover, transplantation outcomes were comparable between the groups. Interestingly, according to our data, there were no differences in terms of abovementioned infectious complications between individuals who received antibiotic prophylaxis and those who did not. Our study has shown that infection complications are independent of the intravenous device and antibiotic prophylaxis. Considering that PCs are not associated with life-threatening complications, they should be considered more frequently in the stem cell transplantation setting.

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Vascular Access

Cited by 2 publications

References 19 publications

Results of a long‐term, prospective study on complications of central venous catheter in pediatric patients with hematologic‐oncologic diseases

Results of a long‐term, prospective study on complications of central venous catheter in pediatric patients with hematologic‐oncologic diseases

Incidence of Catheter-Associated Bloodstream Infections in Stem Cell Recipients—Should We Be “PICCy”?

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