Vas Cannulation with Implanted Sperm Reservoirs for Obstructive Azoospermia or Ejaculatory Failure

Brindley, G. S.; Scott, G. I.; Hendry, W. F.

doi:10.1111/j.1464-410x.1986.tb05920.x

Cited by 44 publications

(18 citation statements)

References 5 publications

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“…Another group of investigators have found normal levels of noradrenalin in the corpora cavernosa of men with SCI (Melman et al, 1980). Thus, according to Brindley et al (1986), the sympathetic system appears to have both erectile and anti-erectile actions (particularly the latter action). The regulation of these opposing actions and their integration with the parasympathetic activity is still under investigation (Brown et al, 2006).…”

Section: Erectionmentioning

confidence: 94%

“…In previous studies some investigators have suggested that the semen analysis in spinal cord injured men, in the chronic phase, demonstrates low (Perkash et al, 1985) to normal (Momen et al, 2007) sperm count and low sperm motility (Perkash et al, 1985;Brindley et al, 1986;Brackett et al, 1995). In the international literature there is limited data on human semen characteristics in the acute phase after SCI.…”

Section: Sperm Parameters After Scimentioning

confidence: 96%

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Erectile function and male reproduction in men with spinal cord injury: a review

et al. 2010

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Spinal cord injury (SCI) in men results in defects in erectile function, ejaculatory process and male reproductive potential. There are alterations in the capacity of men with SCI to achieve reflexogenic, psychogenic and nocturnal erections. The sexual function in different stages after SCI and the types of erections depend mainly on the completeness of the injury and the level of neurological damage. Furthermore, most of the SCI men demonstrate defects concerning the entrance of semen into the posterior urethra and the expulsion of the semen through the penile urethra and the urethral orifice. In addition, SCI men develop defects in the secretory function of the Leydig cells, Sertoli cells and the male accessory genital glands. The overall result is a decreased quality of the semen is recovered either with penile vibratory stimulation (PVS) or with electroejaculation. Nowadays the therapeutic andrological approach of SCI men focuses on achievement of erectile function, recovery of spermatozoa and assisted reproductive technology. The first line of therapy recommended for infertility in SCI men is collection of semen via PVS with concomitant evaluation of total motile sperm yields for assisted conception which may include intravaginal insemination, intrauterine insemination, or in vitro fertilisation/intracytoplasmic sperm injection. Patients failing PVS may be referred for electroejaculation or surgical sperm retrieval.

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Section: Erectionmentioning

confidence: 94%

Section: Sperm Parameters After Scimentioning

confidence: 96%

Erectile function and male reproduction in men with spinal cord injury: a review

et al. 2010

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“…Because of lack of success, we now apply Brindley's sperm reservoir. 19 The reservoir is ā at container with non-pierceable bottom; implanted directly in the lumen of the vas deferens by a small tube. After subcutaneous implantation, it can be punctured percutaneously and semen can be withdrawn.…”

Section: Surgical Methodsmentioning

confidence: 99%

Conservative and surgical semen retrieval in patients with spinal cord injury

et al. 1997

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Assisted semen retrieval was applied in 219 men with spinal cord injury (212 supranuclear, seven infranuclear lesions). Vibrostimulation in supranuclear lesions was successful in 133, and in ®ve more after physostigmine injection. Electroejaculation was successful in all seven infranuclear lesions and in four supranuclear patients failing with vibrostimulation. Eight more supranuclear patients responded to electroejaculation and physostigmine. Surgical retrieval was applied in 27 patients. Nine Wagenknecht spermatoceles showed only one success, from all 18 implanted Brindley reservoirs semen could be collected. Three patients, in whom no pregnancy could be induced after Brindley reservoir implantation, had testicular sperm aspirated. In 109 patients who wanted to have o spring, 73 pregnancies could be induced in 46 couples, leading to 54 births (four twins), 16 abortions and three pregnancies. Conservative semen retrieval was possible in 82 of these men (63 pregnancies in 37 couples) and surgical methods were used in 27 (10 pregnancies in nine couples).

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“…The vasa deferentia are cannulated in the inguinal canal, and the reservoirs are sited under the deep fascia of the anterior abdominal wall just above and lateral to the internal inguinal ring. The reservoir has a self-sealing membrane in front to allow repeated needle puncture, and a rigid back plate and rigid side walls (Brindley et al 1986). When spermatozoa are required for insemination, the reservoir is punctured, the aspirate is discarded, and an equal volume (usually about 0.5 ml) of buffered tissue culture medium such as Earle's solution is instilled into the reservoir.…”

Section: Sperm Reservoirsmentioning

confidence: 99%