Various types of electrochemical biosensors for leukemia detection and therapeutic approaches

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“…In contrast, the levosimendan group showed a significantly lower level (p <0.05) of cTn-I compared to the untreated CLP group, Figure 1. The current study finding of the lower level of cTn-I in the levosimendan group may be attributed to its anti-inflammatory action is linked to its ability to inhibit the Rho-kinase signaling cascade, which may contribute to its cardioprotection against sepsis-induced cardiotoxicity [23]. Another proposed pathway can explain levosimendan cardioprotective effects and lower level of cTn-I by its effect as an inodilator via its work as a calcium sensitizer and activator of ATP-sensitive K channel within the vascular smooth muscle and cardiac mitochondria hence protecting the cardiomyocytes against [13,14].…”

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“…In the overweight group of males and females, the values of calcium/potassium coefficient and zinc/copper coefficient are higher than the normal values, as well as an imbalance in the binding of bio-elements with each other and their levels compared with the normal group, which leads to a violation of the cellular metabolism process [17][18][19][20].…”

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“…In this work, pioglitazone was reported to dramatically decrease the elevation of inflammatory markers (ICAM) in a hypercholesterolemic rabbit atherosclerosis model which suggests that pioglitazone inhibits the vascular inflammation caused by a highcholesterol diet. This finding was made possible by the fact that the rabbits were fed a highcholesterol diet [23][24][25][26][27][28].…”