Various Ca/P ratios of thin calcium phosphate films

Lee, In Seop; Whang, C. N.; Kim, Hyoun Ee; Park, Jong Chul; Song, Jee-Hun; Kim, Soo Ryong

doi:10.1016/s0928-4931(02)00107-8

Cited by 55 publications

(36 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This method, which increases surface roughness, forms TiO 2 on the surface through the oxidation process, and incorporates calcium or phosphorus ions into the surface layer, and is beneficial to osteoblastic cell activity [1,21,22,38]. MAO forms a relatively thick TiO 2 layer by applying a positive voltage above a certain point to the titanium [22].…”

Section: Discussionmentioning

confidence: 99%

“…In this process, the repeated breakdown and regeneration of TiO 2 results in porous and rough surfaces [22,33]. Components of the surface commonly consist of calcium and phosphate and contain a porous structure with pores approximately the size of a micron or submicron, which facilitates osseointegration [14,15,21,23,26]. Moreover, MAO is a simple, controllable, and cost-effective method [22], the latter even more so than HA coatings.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Enhanced Cell Integration to Titanium Alloy by Surface Treatment with Microarc Oxidation: A Pilot Study

Lim

Kwon

Sun

et al. 2009

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

Microarc oxidation (MAO) is a surface treatment that provides nanoporous pits, and thick oxide layers, and incorporates calcium and phosphorus into the coating layer of titanium alloy. We presumed such modification on the surface of titanium alloy by MAO would improve the ability of cementless stems to osseointegrate. We therefore compared the in vitro ability of cells to adhere to MAOed titanium alloy to that of two different types of surface modifications: machined and grit-blasted. We performed energy-dispersive x-ray spectroscopy and scanned electron microscopy investigations to assess the structure and morphology of the surfaces. Biologic and morphologic responses to osteoblast cell lines (SaOS-2) were then examined by measuring cell proliferation, cell differentiation (alkaline phosphatase activity), and avb3 integrin. The cell proliferation rate, alkaline phosphatase activity, and cell adhesion in the MAO group increased in comparison to those in the machined and grit-blasted groups. The osteoblast cell lines of the MAO group were also homogeneously spread on the surface, strongly adhered, and well differentiated when compared to the other groups. This method could be a reasonable option for treating the surfaces of titanium alloy for better osseointegration.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Enhanced Cell Integration to Titanium Alloy by Surface Treatment with Microarc Oxidation: A Pilot Study

Lim

Kwon

Sun

et al. 2009

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

show abstract

“…The dehydration reaction takes place at the beginning of sintering and appears to lose water: dehydration process is reversible below 200 � C, while the process is irreversible above 800 � C and HAP converts into Ca 10 (PO 4 ) 6 …”

Section: Decomposition Mechanismmentioning

confidence: 99%

“…Hydroxypatite (HAP) possesses chemical composition and crystal structure similar to that of human bone [3,4] and excellent biocompatibility, bioactivity and bone conduction capacity. So HAP is an ideal biomimetic bone tissue engineering material [5][6][7][8][9]. However, high brittleness and low anti-pull strength of conventional HAP prevent its application in bearing bone.…”

Section: Introductionmentioning

confidence: 99%

“…However, high brittleness and low anti-pull strength of conventional HAP prevent its application in bearing bone. Therefore, overcoming its brittleness and improving its work reliability for the application of HAP in bearing area has been an issue [5,6,9,10]. Many studies in bioceramic research have been focused on solving the limitation of HAP ceramics and improving its biological properties via exploring the unique nanotechnology [11].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The microstructure evolution of nanohydroxapatite powder sintered for bone tissue engineering

Shuai¹,

Nie

Gao

et al. 2013

Journal of Experimental Nanoscience

View full text Add to dashboard Cite

Nanotechnology has been widely used to overcome the brittleness of coarse ceramics. Laser sintering is an effective approach for the preparation of nanoceramics due to the laser properties such as high energy density and rapid heating. In this study, the nanohydroxypatite (HAP) was used to prepare for artificial bone scaffold using a home-made selective laser sintering (SLS) system. The microstructure and the properties of the sintered nanoHAP are tested with scanning electron microscopy, X-ray diffraction and Fourier transform infrared spectroscopy. We found that the shape of nanoHAP particle changes from long needle-like to spherical or ellipsoidal after sintering, and the HAP particles grow up until they merge together with the increasing temperature. The tendency of preferred orientation reduces and the degree of crystallinity increases with the growth of nanoHAP. HAP dehydroxylation occurs during sintering. HAP decomposes to tetracalcium phosphate and -calcium phosphate when the sintering temperature is over 1354 C (the laser power is 8.75 W). Sintered nanoHAP maintains a high degree of crystalline and nanometre scale when the laser power is 7.50 W, spot radius 2 mm, sintering time 4 s and thickness of the layer is 0.2 mm. This study presented the optimised technology parameters for the preparation of nanoceramics with a novel SLS system and demonstrated that the nanoceramics with nanosize scale can be obtained by this system.

show abstract

Technology of Coating Deposition

Heimann

Lehmann²

2015

Bioceramic Coatings for Medical Implants

View full text Add to dashboard Cite

Various Ca/P ratios of thin calcium phosphate films

Cited by 55 publications

References 23 publications

Enhanced Cell Integration to Titanium Alloy by Surface Treatment with Microarc Oxidation: A Pilot Study

Enhanced Cell Integration to Titanium Alloy by Surface Treatment with Microarc Oxidation: A Pilot Study

The microstructure evolution of nanohydroxapatite powder sintered for bone tissue engineering

Technology of Coating Deposition

Contact Info

Product

Resources

About