Varied Neuro-Psychiatric Manifestations of Farh's Disease (FD):A Report of Two Cases

Abstract

Fahr's syndrome is relatively rare neuropsychiatric disease characterized by bilateral symmetrical basal ganglia intracranial calcification. This disease has varied neuro psychiatric manifestation ranging from neurological, cognitive, and psychiatric manifestations. Here we are representing two cases. In the first case, a 24-year-old male with Fahr's disease (FD), presenting with schizophrenia like psychosis which was not responding to medication, his neurological examination was normal and CT scan of brain revealed symmetrical large areas and foci of calcification in bilateral basal ganglia. Another case was a 70 year old lady presenting with gradual onset of dementia like features, there were no apparent neurological deficit and CT scan brain revealed bilateral basal ganglia calcification. Both the cases on screening did not reveal any evidence in the other family members. Farh's disease (FD) has pronounced positive brain imaging findings along with neuro psychiatric manifestations. We reported sporadic cases of FDs with its neuropsychology and radiological findings.