Varicella-zoster Virus (herpes 3)

Brown, Tricia J.; McCrary, Monica L.

doi:10.1201/9780203910733.ch5

Cited by 7 publications

(8 citation statements)

References 1 publication

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“…Disseminated cutaneous zoster has been defined as more than 20 vesicles outside the area of the primary and adjacent dermatomes [ 1 ]. This complication of zoster has been described in immunocompromised persons (HIV, cancer, patients on immunosuppressive therapy) and reported to be as common as 10% – 40% [ 1 , 2 ]. However, disseminated cutaneous zoster in otherwise healthy persons who are not on immunosuppressive therapy and have no underlying cancer is rare.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with cutaneous dissemination of VZV are at risk of infection of visceral organs, particularly lungs, liver and brain. Other complications include corneal ulceration and post herpetic neuralgia[ 1 ]. Therefore, identification and aggressive treatment of disseminated herpes zoster infection in elderly immunocompetent hosts is important.…”

Section: Discussionmentioning

confidence: 99%

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A rare case of disseminated cutaneous zoster in an immunocompetent patient

et al. 2005

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A rare case of disseminated cutaneous zoster in an immunocompetent patient

et al. 2005

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“…5 Disseminated herpes zoster is defined as more than 20 vesicles outside the area of the primary and adjacent dermatomes, and may or may not involve visceral organs. 6 Cases have been reported in patients with decreased T lymphocyte number or activity such those with HIV or hematological malignancies, as well as patients undergoing chemotherapy. Disseminated zoster cases typically are treated with intravenous acyclovir 10 mg/kg every 8 h for 5-7 days.…”

Section: Discussionmentioning

confidence: 98%

A rare case of disseminated shingles in an immunocompetent patient following a 7-day treatment with oral valacyclovir

Burdett¹,

Mendoza

Arora

et al. 2008

Journal of Clinical Virology

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“…During an illness that suppresses the immune system, the virus is reactivated and travels to the end of the nerve cell, where it causes the symptoms described above [1]. This complication of zoster has been described in immunocompromised persons (HIV, cancer, patients on immunosuppressive therapy) and reported to be as common as 10%-40% [3,4]. However, Herpes zoster oticus in otherwise healthy persons who are not on immunosuppressive therapy and have no underlying cancer is rare.…”

Section: Discussionmentioning

confidence: 99%

“…Patient of VZV without any immunosupression are at risk of infection of visceral organs, particularly lungs, liver and brain. Other complications include corneal ulceration and post herpetic neuralgia [3]. Therefore, identification and aggressive treatment of disseminated herpes zoster infection in elderly immunocompetent hosts is important.…”

Section: Discussionmentioning

confidence: 99%

A rare case of Herpes zoster oticus in an immunocompetent patient

Dhavalshankh¹,

Dhavalshankh²,

Mhasvekar³

2012

Our Dermatol Online

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IntroductionRamsay Hunt syndrome (RHS) is first described by James Ramsay Hunt in 1907 [1]. It is caused by the reactivation of latent varicella-zoster virus (VZV) that has remained dormant within sensory root ganglia (commonly the geniculate ganglion) of the sensory branch of the facial nerve. Involvement of sensory branch of the geniculate ganglion of facial nerve leads Herpes zoster (HZ) oticus which is also known as RHS. Individuals with decreased cell-mediated immunity resulting from carcinoma, radiation therapy, chemotherapy or human immunodeficiency virus (HIV) infection are at greater risk for reactivation of latent VZV. Physical stress and emotional stress often are cited as precipitating factors. Incidence and clinical severity increases when host immunity is compromised. However it is uncommon to see Herpes zoster oticus in healthy individuals. In this report, we describe the clinical course of a patient who presented with Herpes zoster oticus in the absence of a known immunosuppressive condition. A brief review of literature on this topic is also presented. Case ReportA previously healthy 65-year old man presented with a 3-days history of vesicular lesions with erythematous base on neck. It was followed by the spread of vesicular eruption to involve external external auditory meatus of right side, and pinna over next 2-days. These are fluid filled vesicular eruptions which bust and break down on 2nd-3rd day with subsequent scab formation. There is no facial weakness. On examination, there was no lower motor neuron facial palsy. A neurologic examination revealed no weakness in the marginal mandibular branch of the left facial nerve. There is no any sign of loss of ipsilateral nasolabial fold or weakness in the temporal branch of the facial nerve. There were painful adherent crusts and scabs in left conchae and external auditory meatus (Fig. 1), associated with unclear hearing of left ear. The oral cavity and oropharynx were normal. Ocular examination demonstrated no nystagmus and normal conjunctiva. He has given history of stressful life events (sudden 3 deaths in family) in past 4 months. Review of systems was negative. The patient is not able to tell history of chickenpox during childhood or any recent exposure to it. There was no past history of diabetes, cardiac or pulmonary disease or lymphoma. The patient has not been on immunosuppressive or other medications. There is history of Psoriasis 2 years back showing on and off symptoms but on regular treatment. Patient is alcoholic, habit of tobacco chewing and occasional Pan chewing. On examination, the patient was afebrile (37.4°C). He had vesicles but not pustules, with crusting and swelling, in the distribution of the cervical division of VII (facial) cranial nerve. The left pinna is swollen, tender and red. There was no tympanic membrane involvement. Vesicles and scabs in various stages were also present lateral side of neck, in front of sternum and external ear ( Fig. 1) and behind Right pinna (Fig. 2) AbstractHerpes zoster oticus in healthy pe...

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Varicella-zoster Virus (herpes 3)

Cited by 7 publications

References 1 publication

A rare case of disseminated cutaneous zoster in an immunocompetent patient

A rare case of disseminated cutaneous zoster in an immunocompetent patient

A rare case of disseminated shingles in an immunocompetent patient following a 7-day treatment with oral valacyclovir

A rare case of Herpes zoster oticus in an immunocompetent patient

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