Varicella-like exanthem as a specific COVID-19–associated skin manifestation: Multicenter case series of 22 patients

Marzano, Angelo Valerio; Genovese, Giovanni; Fabbrocini, Gabriella; Pigatto, Paolo D.; Monfrecola, Giuseppe; Piraccini, Bianca Maria; Veraldi, Stefano; Rubegni, Pietro; Cusini, Marco; Caputo, Valentina; Rongioletti, Franco; Berti, Emilio; Calzavara‐Pinton, Piergiacomo

doi:10.1016/j.jaad.2020.04.044

Cited by 335 publications

(435 citation statements)

References 5 publications

(1 reference statement)

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“…Direct immunofluorescence was negative, including antibody–fluorophore conjugates to IgG, IgM, IgA, complement proteins C1q, C3, and C4c, and fibrinogen. This histology is similar to that previously reported 5 …”

Section: Figuresupporting

confidence: 92%

Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic

et al. 2020

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Section: Figuresupporting

confidence: 92%

Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic

et al. 2020

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“…Recalcati et al, 8 who conducted the first study regarding the cutaneous findings of COVID‐19, reported varicella‐like lesions in one of 18 patients. Marzona et al 19 also identified varicella‐like eruption in 12 out of 22 patients with COVID‐19 and they concluded that this type of eruption may be a specific manifestation of COVID‐19. Casas Galvan et al 7 described small monomorphic vesicles located on the trunk in 9% of 375 patients with COVID‐19.…”

Section: Papulovesicular Eruptionsmentioning

confidence: 97%

Cutaneous manifestations of COVID ‐19: A review of the published literature

Elmas

Demirbaş

Özyurt

et al. 2020

Dermatologic Therapy

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COVID‐19 is a highly contagious respiratory tract infection caused by severe acute respiratory syndrome coronavirus 2. COVID‐19 outbreak, which caused thousands of deaths, has been declared a pandemic by the World Health Organization in March 2020. The infection has been reported to demonstrate different types of cutaneous manifestations including urticarial, maculopapular, papulovesicular, purpuric, livedoid, and thrombotic‐ischemic lesions. Given the high mortality rate of the infection, timely and accurate identification of relevant cutaneous manifestations may play a key role in the early diagnosis and management. In this study, we provide a review with a focus on the reported cutaneous manifestations of COVID‐19.

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“…5,6 Italian researchers described 22 patients with scattered or diffuse varicella-like vesiculopapular eruptions, representing the largest cohort of COVID-19 patients published thus far with similar cutaneous eruptions. 6 The authors concluded that these vesiculopapular eruptions were specifi c to COVID-19, stressing that no patient in their cohort had been exposed to new medications in the 15 days before eruption onset. Median latency time from COVID-19 systemic symptoms to the rash was 3 days, and the median duration of skin manifestations was 8 days.…”

Section: ■ Morbilliform Rashmentioning

confidence: 99%

Skin manifestations of COVID-19

Young

Fernandez

2020

CCJM

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The statements and opinions expressed in COVID-19 Curbside Consults are based on experience and the available literature as of the date posted. While we try to regularly update this content, any offered recommendations cannot be substituted for the clinical judgment of clinicians caring for individual patients. ABSTRACT Cutaneous manifestations, a well-known effect of viral infections, are beginning to be reported in patients with COVID-19 disease. These manifestations most often are morbilliform rash, urticaria, vesicular eruptions, acral lesions, and livedoid eruptions. Some of these cutaneous manifestations arise before the signs and symptoms more commonly associated with COVID-19, suggesting that they could be presenting signs of COVID-19.

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Varicella-like exanthem as a specific COVID-19–associated skin manifestation: Multicenter case series of 22 patients

Cited by 335 publications

References 5 publications

Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic

Acral purpuric lesions associated with coagulation disorders during the COVID‐19 pandemic

Cutaneous manifestations of COVID ‐19: A review of the published literature

Skin manifestations of COVID-19

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