Varicella‐Associated Invasive Group A Streptococcal Disease in Alberta, Canada—2000–2002

Abstract

We determined the incidence of invasive group A streptococcal (GAS) disease among children < or =14 years of age in Alberta, Canada, with a focus on infections associated with varicella. During 2000-2002, there were 71 cases of invasive GAS disease among patients in this age group. Fourteen cases occurred in children with varicella (19.7%), for an annual incidence of 0.73 varicella-associated cases per 100,000 children. Necrotizing fasciitis was not noted in patients with invasive GAS disease and varicella.

Necrotizing fasciitis in children: diagnostic and therapeutic aspects

“…Initiating factors reported in the literature include minor and major trauma, surgical wounds, and varicella lesions [1][2][3][4][5][6][7]. In agreement with the literature, varicella lesions and intramuscular injection sites were the most common initiating factors among our patients [1][2][3][4][5][7][8][9][10]. Dermal colonization of S. pyogenes during upper respiratory tract infection and interruption of dermal integrity by intramuscular injections and application of a cream containing menthol to the cervical region resulted in development of NF in 3 of our patients.…”

“…It has been reported in 0.08 per 100,000 children per year [3]. However, an increasing incidence of NF caused by invasive Streptococcus pyogenes has been reported from various parts of world, during the past several years [8][9][10].…”

Characterisation of Streptococcal Isolates from a Tertiary Care Centre –A One Year Study

“…Tyrrell GJ et al in his study isolated 14 cases of invasive GAS in children with Varicella. 4 In the present study GAS In the present study, Streptococcal infections were more common in males than in females. Out of 212 isolates 61.79% were isolated from male patients and 38.21% were isolated from female patients.…”

Differences in the epidemiology between paediatric and adult invasiveStreptococcus pyogenesinfections

“…This surveillance covered both adult and paediatric cases and presented for the first time data from Greece, as part of the Strep-EURO initiative [1]. Preliminary observations regarding the epidemiology within each age group led us to further investigate possible epidemiological and clinical differences of iGAS infections between the two groups, during the extended period of 2003-2007, as similar comparable data are scarce in the literature and the majority of previous studies simply presented results on overall iGAS infections, or compared invasive and superficial infections [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17]. In addition, typing of the isolates using emm-gene sequencing was performed, in order to assess strain variation.…”