Variations in the reported prevalence of gastroesophageal reflux disease in Taiwan

Chang, Full‐Young

doi:10.1016/j.jcma.2012.02.003

Cited by 7 publications

(7 citation statements)

References 14 publications

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“…These studies from Taiwan7 and India8 were population-based studies that used validated GORD questionnaires. The prevalence in the Taiwan study was higher than previously reported, which was as low as 3.9% 9. Another study of asymptomatic health screening subjects from Taiwan showed a prevalence rate of 12.0% 10.…”

Section: Resultscontrasting

confidence: 64%

Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus

Fock

Talley

Goh

et al. 2016

Gut

153

214

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Section: Resultscontrasting

confidence: 64%

Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus

Fock

Talley

Goh

et al. 2016

Gut

153

214

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“…Some variation in GERD prevalence, ranging from 3.9–25%, has been reported in Taiwan. The difference was usually determined by the used definitions, study patients, and intra- and inter-observer inconsistencies regarding endoscopic diagnosis [12]. …”

Section: Discussionmentioning

confidence: 99%

Risk of acute myocardial infarction in patients with gastroesophageal reflux disease: A nationwide population-based study

et al. 2017

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ObjectiveGastroesophageal reflux disease (GERD) is a common disease which can cause troublesome symptoms and affect quality of life. In addition to esophageal complications, GERD may also be a risk factor for extra-esophageal complications. Both GERD and coronary artery disease (CAD) can cause chest pain and frequently co-exist. However, the association between GERD and acute myocardial infarction (AMI) remain unclear. The purpose of the study was to compare the incidence of acute myocardial infarction in GERD patients with an age-, gender-, and comorbidity matched population free of GERD. We also examine the association of the risk of AMI and the use of acid suppressing agents in GERD patients.MethodsWe identified patients with GERD from the Taiwan National Health Insurance Research Database. The study cohort comprised 54,422 newly diagnosed GERD patients; 269,572 randomly selected age-, gender-, comorbidity-matched subjects comprised the comparison cohort. Patients with any prior CAD, AMI or peripheral arterial disease were excluded. Incidence of new AMI was studied in both groups.ResultsA total 1,236 (0.5%) of the patients from the control group and 371 (0.7%) patients from the GERD group experienced AMI during a mean follow-up period of 3.3 years. Based on Cox proportional-hazard model analysis, GERD was independently associated with increased risk of developing AMI (hazard ratio (HR) = 1.48; 95% confidence interval (CI): 1.31–1.66, P < 0.001). Within the GERD group, patients who were prescribed proton pump inhibitors (PPIs) for more than one year had slightly decreased the risk of developing AMI, compared with those without taking PPIs (HR = 0.57; 95% CI: 0.31–1.04, P = 0.066).ConclusionsThis large population-based study demonstrates an association between GERD and future development of AMI, however, PPIs use only achieved marginal significance in reducing the occurrence of AMI in GERD patients. Further prospective studies are needed to evaluate whether anti-reflux medication may reduce the occurrence of acute ischemic event in GERD patients.

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“…Each member of the GERD and comparison matched pair was followed from the same index date and all participants were observed until they were diagnosed with schizophrenia (ICD-9-CM code: 295), depressive disorder (ICD-9-CM codes: 296. 2 ; or until death, withdrawal from the NHI system, or December 31, 2009. The primary clinical outcomes were psychiatrist-diagnosed schizophrenia, depressive disorder, bipolar disorder, anxiety disorder, and sleep disorder.…”

Section: Study Populationmentioning

confidence: 99%

“…It is one of the most common gastrointestinal (GI) disorders with a prevalence of 8.1%-27.8% in North America, 8.8%-25.9% in Europe and 0.69%-25% in Taiwan [2,3]. Typical GERD symptoms affect patients' quality of life and overall work productivity, and have caused health care costs to increase in Asian countries [4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Risk of psychiatric disorders following gastroesophageal reflux disease: A nationwide population-based cohort study

You

Perng

et al. 2015

European Journal of Internal Medicine

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Variations in the reported prevalence of gastroesophageal reflux disease in Taiwan

Cited by 7 publications

References 14 publications

Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus

Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett's oesophagus

Risk of acute myocardial infarction in patients with gastroesophageal reflux disease: A nationwide population-based study

Risk of psychiatric disorders following gastroesophageal reflux disease: A nationwide population-based cohort study

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