Variations in certain properties of bovine cervical mucus during the oestrous cycle

Blair, G. W. Scott; Folley, S. J.; Malpress, F. H.; Coppen, F. M. V.

doi:10.1042/bj0351039

Cited by 43 publications

(9 citation statements)

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“…When caused to flow along a 2 mm. horizontal capillary under pressure (in an apparatus similar to that used by Scott Blair, Folley, Malpress & Coppen (1941) for testing the flow-elasticity of * bovine cervical mucus), they show marked recoil when the pressure is suddenly released.…”

Section: Methodsmentioning

confidence: 99%

Crystalline Bacterial Catalase

Herbert

Pinsent

1947

Nature

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spectroscope the narrow width of the absorption band in the red led to an overestimate of its intensity. Others have also been misled by the narrowness of the first absorption band; thus Grinstein, Schwartz & Watson (1945) describe the relative intensities of the absorption bands of coproporphyrin I as IV, III, I and II in decreasing order.The eluate containing the second porphyrin zone was evaporated to dryness, and after recrystallization from chloroform and methanol gave 7-1 mg. of the typical hairlike crystals of uroporphyrin I octamethyl ester (m.p. 288°). In chloroform, this ester showed absorption bands at 625-7, 576-7, 536-5 and 503-6 mi., intensity IV>III>II>I (Hartridge reversion spectroscope). The third porphyrin zone has not yet been identified. DISCUSSIONThe isolation of coproporphyrin III ester in relatively enormous quantities in the large-scale production of purified diphtheria toxoid provides an abundant and hitherto unexplored source of coproporphyrin III, which wiU be of the greatest value in the investigation of the metabolic relationships of this material in the intact animal. The production of small quantities of uroporphyrin I provides yet another example of the so-called dualism of the porphyrins, attention to which was first drawn by Fischer (1937). In the light of present knowledge it is not possible to speculate on the significance of this dualism to the economy of the organism. The implications suggested by Pappenheimer (1947) regarding the relationship of the production of porphyrin to toxin formation will be the subject of a separate paper to be published elsewhere. SUMMARYCoproporphyrin III tetramethyl ester in large yield and uroporphyrin I octamethyl ester in very small yield have been prepared from toxic culture filtrates of Corynebacterium diphtheriae.

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Section: Methodsmentioning

confidence: 99%

Crystalline Bacterial Catalase

Herbert

Pinsent

1947

Nature

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“…In the natural world, the extensional viscosity contributes to the properties required from glues used on spider webs and by carnivorous plants, [25][26][27] protein solutions used by spiders and insects for the spinning of silk, 28 and that controls many of the functions of mucus. 12,13,29,30 The extensional viscosity is recognized as a fundamental material function that needs to be quantified in order to enable a full predictive description of the response of a particular fluid to an arbitrary applied deformation through the development of an accurate constitutive equation. 31,32 However, the extensional viscosity has proved to be an extremely difficult and elusive quantity to measure.…”

Section: Introductionmentioning

confidence: 99%

Microfluidic extensional rheometry using stagnation point flow

Haward

2016

Biomicrofluidics

102

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Characterization of the extensional rheometry of fluids with complex microstructures is of great relevance to the optimization of a wide range of industrial applications and for understanding various natural processes, biological functions, and diseases. However, quantitative measurement of the extensional properties of complex fluids has proven elusive to researchers, particularly in the case of low viscosity, weakly elastic fluids. For some time, microfluidic platforms have been recognized as having the potential to fill this gap and various approaches have been proposed. This review begins with a general discussion of extensional viscosity and the requirements of an extensional rheometer, before various types of extensional rheometers (particularly those of microfluidic design) are critically discussed. A specific focus is placed on microfluidic stagnation point extensional flows generated by cross-slot type devices, for which some important developments have been reported during the last 10 years. Additional emphasis is placed on measurements made on relevant biological fluids. Finally, the operating limits of the cross-slot extensional rheometer (chiefly imposed by the onset of elastic and inertial flow instabilities) are discussed.

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“…The most important differences, however, are in the nitrogenous components. The mucin present in oestrus contains little nitrogen, as pointed out by Scott Blair et al (1941). It contains relatively more carbohydrate and less protein and glucosamine (when calculated on an ash-free basis) than the two other types; it gives no colour with the ninhydrin reagent and a negative or feeble biuret reaction, and probably contains substances which might be classed as mucopolysaccharides (cf.…”

Section: % Of Dry Mattermentioning

confidence: 95%

The composition of bovine cervical mucins and their reaction with oxidizing agents

Boyland

1946

Biochemical Journal

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cases the sulphur atoms permit the synthesis of unique molecular types, but it is probably the molecule as a whole and not some special attribute of the sulphur atoms which is responsible for the biological effect. SUMMARY A series of xanthic, dithiocarbamic, thiocyanic and isothiocyanic acid derivatives, together with some oxygen analogues and benzthiazole derivatives, have been prepared and their relative fungistatic activities recorded. In many of the compounds the sulphur atoms can be replaced by oxygen without marked loss of fungistatic power. The ldwer xanthates and certain substituted arylisothiocyanates have very high fungistatic activities. The authors are indebted to several colleagues for the preparation of certain compounds, for helpful discussions and also for the carrying out of the biological testing.

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Variations in certain properties of bovine cervical mucus during the oestrous cycle

Cited by 43 publications

References 2 publications

Crystalline Bacterial Catalase

Crystalline Bacterial Catalase

Microfluidic extensional rheometry using stagnation point flow

The composition of bovine cervical mucins and their reaction with oxidizing agents

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