Variations in Blood Copper and Possible Mechanisms During Pregnancy

Guan, Lihua; Wang, Yifei; Lin, Liling; Zou, Yutong; Qiu, Ling

doi:10.1007/s12011-023-03716-x

Cited by 2 publications

(1 citation statement)

References 78 publications

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“…In contrast, copper levels increase during pregnancy as gestational age progresses, driven by rising estrogen levels and ceruloplasmin production [ 6 ]. This ensures adequate serum copper levels for both the mother and the baby.…”

Section: Introductionmentioning

confidence: 99%

Correlation of Zinc and Copper Levels In Mothers and Cord Blood of Neonates With Prematurity and Intrauterine Growth Pattern

Garlapati,

Venigalla,

Mane

et al. 2024

Cureus

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Background Trace elements like zinc and copper are indispensable for human growth and development, exerting significant influence on a multitude of physiological processes. Acting as pivotal components for transcription factors and catalytic cofactors for enzymes, these elements play essential roles in cellular differentiation and maturation Objective The objective of this study was to study serum zinc and copper levels in mothers and neonates in relation to prematurity and intrauterine growth retardation (IUGR). Methods This was a cross-sectional study that included 100 mothers who met the inclusion criteria. Maternal history was recorded, and gestational age was estimated using the New Ballard scoring system. Maternal and cord blood samples were taken for zinc and copper analysis. Results The comparison of maternal copper and zinc levels between term and preterm neonates revealed a statistically significant difference with both trace elements found in less concentration in preterm when compared to the term patients (p= 0.03 for Zinc; 0.0001 for copper). We also report a statistically significant difference in maternal and cord blood copper and zinc levels in cases with IUGR compared to normal neonates. Conclusion The findings show that maternal zinc and copper levels are critical for the intrauterine growth of the fetus and for appropriate gestational age

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Section: Introductionmentioning

confidence: 99%

Correlation of Zinc and Copper Levels In Mothers and Cord Blood of Neonates With Prematurity and Intrauterine Growth Pattern

Garlapati,

Venigalla,

Mane

et al. 2024

Cureus

View full text Add to dashboard Cite

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Multiomics: Functional Molecular Biomarkers of Micronutrients for Public Health Application

Allen,

Fenech,

LeVatte

et al. 2024

Annual Review of Nutrition

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Adequate micronutrient intake and status are global public health goals. Vitamin and mineral deficiencies are widespread and known to impair health and survival across the life stages. However, knowledge of molecular effects, metabolic pathways, biological responses to variation in micronutrient nutriture, and abilities to assess populations for micronutrient deficiencies and their pathology remain lacking. Rapidly evolving methodological capabilities in genomics, epigenomics, proteomics, and metabolomics offer unparalleled opportunities for the nutrition research community to link micronutrient exposure to cellular health; discover new, arguably essential micronutrients of microbial origin; and integrate methods of molecular biology, epidemiology, and intervention trials to develop novel approaches to assess and prevent micronutrient deficiencies in populations. In this review article, we offer new terminology to specify nutritional application of multiomic approaches and encourage collaboration across the basic to public health sciences to advance micronutrient deficiency prevention.

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Variations in Blood Copper and Possible Mechanisms During Pregnancy

Cited by 2 publications

References 78 publications

Correlation of Zinc and Copper Levels In Mothers and Cord Blood of Neonates With Prematurity and Intrauterine Growth Pattern

Correlation of Zinc and Copper Levels In Mothers and Cord Blood of Neonates With Prematurity and Intrauterine Growth Pattern

Multiomics: Functional Molecular Biomarkers of Micronutrients for Public Health Application

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