2003
DOI: 10.1002/mrm.10624
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Variation of the relaxographic “shutter‐speed” for transcytolemmal water exchange affects the CR bolus‐tracking curve shape

Abstract: Contrast reagents (CRs) may enter the tissue interstitium for a period after a vascular bolus injection. As the amount of interstitial CR increases, the longitudinal relaxographic NMR "shutter-speed" (T

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Cited by 173 publications
(382 citation statements)
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References 41 publications
(174 reference statements)
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“…The SM assumes that the equilibrium water intercompartmental exchange systems remain in the FXL: it is FXLconstrained (FXL-c). We also used the FXR-and SXR-allowed (FXR-a and SXR-a) versions of the first-generation ShutterSpeed Model (SSM1), BOLus Enhanced Relaxation Overview (BOLERO) (8,11). In the SM analyses, the parameters varied are K trans and v e , while the i value is (implicitly) zero (11,13,14).…”
Section: Resultsmentioning
confidence: 99%
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“…The SM assumes that the equilibrium water intercompartmental exchange systems remain in the FXL: it is FXLconstrained (FXL-c). We also used the FXR-and SXR-allowed (FXR-a and SXR-a) versions of the first-generation ShutterSpeed Model (SSM1), BOLus Enhanced Relaxation Overview (BOLERO) (8,11). In the SM analyses, the parameters varied are K trans and v e , while the i value is (implicitly) zero (11,13,14).…”
Section: Resultsmentioning
confidence: 99%
“…The model has the constraints that i is vanishingly small (the FXL) and that the transverse relaxation factor [exp(ϪTE⅐R 2 ‫ء‬ )] ϭ 1. The dashed curve shows the characteristic undershoot at the beginning, followed by overshoot and then undershoot during the washout (11,13,14). The K trans and v e parameter values from this fitting are listed in Table 1.…”
Section: Resultsmentioning
confidence: 99%
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