Variation of Peripheral Blood-based Biomarkers for Response of Anti-PD-1 Immunotherapy in Lung Cancer
Feng Yan,
Xiaoming Wang,
Dayu Chen
et al.
Abstract:The therapeutic regimen of immune checkpoint inhibitors (ICIs) has been a great achievement of elevated survival results in lung cancer, but only a small proportion of patients can benefit from it in the long term. Therefore, peripheral blood-based biomarkers which could effectively predict the efficacy of anti-PD-1/PD-L1 immunotherapy are crucial for selection of dosage regimen. Here we compared the performance of four machine learning models and chose lightGBM model to screen and analyze the most important b… Show more
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