Variation of corneal thickness with age in young New Zealanders

Abstract

The central thickness of the left eyes of 1082 New Zealand students aged 5 to 20 years were measured using optical pachometry. No significant variation in corneal thickness was found with increasing age. The mean corneal thickness of the left eye was 540 +/- 25 microns. No significant differences in corneal thickness were found when the effects of sex or cultural groupings were examined. Corneal thickness appears to remain constant between the age of 5 and 20 years, irrespective of sex or cultural grouping.

Factors Influencing Central Corneal Thickness in a Turkish Population

“…19,20 A few studies found CCT values of the left eye to be greater than those of the right eye. 16,18 In our study, gender did not seem to affect CCT as it did in several other studies. 1,15,16,32,33 Brandt et al found greater CCT values for women than for men.…”

“…16,18 In our study, gender did not seem to affect CCT as it did in several other studies. 1,15,16,32,33 Brandt et al found greater CCT values for women than for men. 18 In the study of Alsbirk et al, CCT readings of Caucasian men and Eskimo women were found to be greater than those of their gender counterparts.…”

Identifying relationships between tomography-derived corneal thickness, curvature, and diameter and in vivo confocal microscopic assessment of the endothelium in healthy corneas of young adults

“…34 Similar to the observations of previous reports, we identified no significant difference in CCT based on gender in this study. [35][36][37] The relationship between CCT and age has been extensively studiedFalthough the majority of authors report a gradual decrease in CCT with advancing age after infancy, [38][39][40][41][42] in contrast, others have reported no change or an increase in CCT with advancing age. 36,43 The relationship between significant endothelial dysfunction and increased corneal thickness is well established, 3,[44][45][46] and recognized causes of increased corneal thickness include anterior segment disease and previous intraocular surgery.…”

Central corneal thickness in children—does it help or hinder our evaluation of eyes at risk for glaucoma?

“…The average CCT of normal children is similar to that of adults, [8][9][10][11][12] and there is little reported effect of age on CCT. As in adults, race seems to affect average CCT in normal eyes-hence average CCT appears to be lower in normal black children than in normal white children.…”

“…The authors report that while there is a huge range of CCT in this group (486-705 m), the average CCT (559 m) is similar to that reported for normal children (approximately 540-560 m). [8][9][10][11][12] The study reports a modest correlation between measured IOP ( by air-puff and Perkins tonometry measured under anesthesia) and CCT and also attempts to correlate CCT and degree of clinical corneal opacification. The authors recognize the significant limitations of their findings but nonetheless correctly identify an interesting ophthalmic feature in MPS-1 after bone marrow transplant-namely, the corneal findings, CCT among them.…”