Variation in Schlemm's Canal Diameter and Location by Ultrasound Biomicroscopy

Irshad, Farhan A.; Mayfield, Melinda S.; Zurakowski, David; Ayyala, Ramesh S.

doi:10.1016/j.ophtha.2009.09.041

Cited by 50 publications

(34 citation statements)

References 6 publications

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“…Consequently special attention was given to their 3D reconstruction. Results of SC thickness were compared to those found by Irshad et al [10], where the SC diameter was measured using Ultrasound Biomicroscopy in vivo. The average diameter values reported by Irshad and colleagues (121 ± 45 m) were lower than our results.…”

Section: Discussionmentioning

confidence: 99%

3D simulation of the aqueous flow in the human eye

Villamarin

Roy

Hasballa

et al. 2012

Medical Engineering & Physics

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Section: Discussionmentioning

confidence: 99%

3D simulation of the aqueous flow in the human eye

Villamarin

Roy

Hasballa

et al. 2012

Medical Engineering & Physics

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“…Ultrasound probe) at the 12 o´clock position by Irshad et al [4]. The average canal diameter was 121 μm (± 45 μm).…”

Section: Sc Dimension Was Investigated By Ultrasound (80-mhz Andmentioning

confidence: 99%

Schlemms Canal in OCT Images in Glaucoma Patients and Healthy Subjects

Forgácová¹,

Lešták²,

Pitrová³

et al. 2013

J Clin Exp Ophthalmol

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“…The porcine eye has a series of CCs instead of a single large circumferential SC [25]. Compared with porcine eye, rat eye is smaller as well as the size of SC and aqueous veins [26, 27]. The resolution of image is the limitation of imaging quality in the drainage channels.…”

Section: Discussionmentioning

confidence: 99%

Microstructure visualization of conventional outflow pathway and finite element modeling analysis of trabecular meshwork

et al. 2016

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BackgroundThe intraocular pressure (IOP) is maintained through a dynamic equilibrium between the production and drainage of aqueous humor. Elevation of intraocular pressure is mainly caused by the blocking of aqueous humor outflow pathway. Therefore, it is particularly important to study the structure of drainage pathway and the effect of ocular hypertension at the process of aqueous humor outflow.MethodsConventional drainage pathway of aqueous humor, including trabecular meshwork (TM), Schlemm’s canal (SC) and aqueous vein, were imaged by using trans-scleral imaging method with lateral resolution of 2 μm. For quantitative assessment, the morphological parameters of the TM were measured with different IOP levels via a combination of measurements and simulations.ResultsImages of the TM and the adjacent tissues were obtained. The porosity of TM with normal intraocular pressure varies from 0.63 to 0.74 as the depth increases, while in high IOP it is changed from 0.44 to 0.59. The diameter of aqueous vein varies from 32 to 43 μm, and is smaller than that of SC, which varies from 48 to 64.67 μm.ConclusionsOur research provides a non-contact method to visualize the microstructure of tissue for clinical examination associated with the blocking of the outflow pathway of aqueous humor in humans. The three-dimensional (3D) microstructures of limbus and the results of finite element modeling analysis of the TM model will serve for the future evaluation of new glaucoma surgical techniques.

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Variation in Schlemm's Canal Diameter and Location by Ultrasound Biomicroscopy

Cited by 50 publications

References 6 publications

3D simulation of the aqueous flow in the human eye

3D simulation of the aqueous flow in the human eye

Schlemms Canal in OCT Images in Glaucoma Patients and Healthy Subjects

Microstructure visualization of conventional outflow pathway and finite element modeling analysis of trabecular meshwork

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