Variation in isolates of Sclerotinia sclerotiorum (Lib.) de Bary causing white mold disease in Bangladesh crops

Nahar, M. S.; Naher, Najmun; Alam, Mehtab; Hossain, Mohammad Shakhawat; Mian, M. Y.; Miller, Sally A.

doi:10.1016/j.cropro.2019.104849

Cited by 3 publications

(1 citation statement)

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“…Invasive hyphae of S. sclerotiorum intracellularly colonize host tissues while host cell death and tissue maceration originate at the center of the site of initial infection. This difficult-to-control fungus notoriously devastates global food security and recently spread to previously uninhabited geographical niches ( 64 – 67 ). The global infection transcriptome was investigated based on the spatial organization of invasive hyphae relative to that of the central mycelium cells.…”

Section: Transcriptomicsmentioning

confidence: 99%

Fun(gi)omics: Advanced and Diverse Technologies to Explore Emerging Fungal Pathogens and Define Mechanisms of Antifungal Resistance

Ball

Langille

Geddes‐McAlister

2020

mBio

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The landscape of infectious fungal agents includes previously unidentified or rare pathogens with the potential to cause unprecedented casualties in biodiversity, food security, and human health. The influences of human activity, including the crisis of climate change, along with globalized transport, are underlying factors shaping fungal adaptation to increased temperature and expanded geographical regions. Furthermore, the emergence of novel antifungal-resistant strains linked to excessive use of antifungals (in the clinic) and fungicides (in the field) offers an additional challenge to protect major crop staples and control dangerous fungal outbreaks. Hence, the alarming frequency of fungal infections in medical and agricultural settings requires effective research to understand the virulent nature of fungal pathogens and improve the outcome of infection in susceptible hosts. Mycology-driven research has benefited from a contemporary and unified approach of omics technology, deepening the biological, biochemical, and biophysical understanding of these emerging fungal pathogens. Here, we review the current state-of-the-art multi-omics technologies, explore the power of data integration strategies, and highlight discovery-based revelations of globally important and taxonomically diverse fungal pathogens. This information provides new insight for emerging pathogens through an in-depth understanding of well-characterized fungi and provides alternative therapeutic strategies defined through novel findings of virulence, adaptation, and resistance.

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Section: Transcriptomicsmentioning

confidence: 99%