Objective-To determine the test-retest reliability of drug-induced sleep endoscopy (DISE).Methods-Prospective cohort study. Patients with OSA underwent two separate DISE examinations. The following outcomes were measured: a global assessment of obstruction at the palate and/or hypopharynx; the degree of obstruction at the palate and hypopharynx; and contribution of individual structures (palate, tonsils, tongue, epiglottis, and lateral pharyngeal walls) to obstruction.Results-32 patients underwent two separate DISE examinations. The apnea-hypopnea index was 40.7±21.1, and the lowest oxygen saturation was 79.8±17.4%. Point estimates for the intraclass correlation coefficient analogs related to palatal obstruction ranged from 0.41-0.89; related to the hypopharyngeal airway, the point estimates ranged from 0.57-0.84.
Conclusion-The test-retest reliability of DISE appears good, especially in the evaluation of the hypopharyngeal airway. Larger studies can generate more-precise confidence interval estimates and test the generalizability of these findings.