Variable Number Tandem Repeat (VNTR) analysis reveals genetic diversity within Mycoplasma mycoides mycoides Small Colony isolates from Nigeria

Nwankpa, Nicholas D.; Manso-Silván, Lucía; Lorenzon, Sophie; YaYa, Aboubakar; Lombin, L.H.; Thiaucourt, François

doi:10.1016/j.vetmic.2010.05.020

Cited by 3 publications

(2 citation statements)

References 3 publications

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“…Several studies have attempted to resolve the evolutionary relationships between the members of the ‘ M. mycoides cluster’ [6], [7], [8], or to infer the evolutionary history of single members within the cluster [9], [10], [11]. However, despite the recent publication of complete genome data from single isolates belonging to the different lineages [12], a comprehensive overview of the evolutionary history of the ‘ M. mycoides cluster’ and genetic relationship between populations is still lacking.…”

Section: Introductionmentioning

confidence: 99%

The Origin of the ‘Mycoplasma mycoides Cluster’ Coincides with Domestication of Ruminants

et al. 2012

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The ‘Mycoplasma mycoides cluster’ comprises the ruminant pathogens Mycoplasma mycoides subsp. mycoides the causative agent of contagious bovine pleuropneumonia (CBPP), Mycoplasma capricolum subsp. capripneumoniae the agent of contagious caprine pleuropneumonia (CCPP), Mycoplasma capricolum subsp. capricolum, Mycoplasma leachii and Mycoplasma mycoides subsp. capri. CBPP and CCPP are major livestock diseases and impact the agricultural sector especially in developing countries through reduced food-supply and international trade restrictions. In addition, these diseases are a threat to disease-free countries. We used a multilocus sequence typing (MLST) approach to gain insights into the demographic history of and phylogenetic relationships among the members of the ‘M. mycoides cluster’. We collected partial sequences from seven housekeeping genes representing a total of 3,816 base pairs from 118 strains within this cluster, and five strains isolated from wild Caprinae. Strikingly, the origin of the ‘M. mycoides cluster’ dates to about 10,000 years ago, suggesting that the establishment and spread of the cluster coincided with livestock domestication. In addition, we show that hybridization and recombination may be important factors in the evolutionary history of the cluster.

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Section: Introductionmentioning

confidence: 99%

The Origin of the ‘Mycoplasma mycoides Cluster’ Coincides with Domestication of Ruminants

et al. 2012

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“…In the recent years VNTR typing systems have been employed in genetic studies of mycoplasmas including Mycoplasma hyorhinis (15), Mycoplasma hyopneumoniae (16), Mycoplasma bovis (17), Mycoplasma californicum (18) and Mycoplasma mycoides (19). Similarly, MLST genotyping has been used in epidemiological studies of several Mycoplasma species including M. agalactiae (20), Mycoplasma bovis (20).…”

Section: Introductionmentioning

confidence: 99%

Homogeneity of Mycoplasma agalctiae vaccine strains in an agalaxy- high-burden environment

Kabiri¹,

Pourbakhsh²,

Norouzi³

et al. 2019

IJM

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Background and Objectives: Interrogation of the genomic relations between Iranian Mycoplasma agalactiae vaccine strains of Taliqan, Lorestan and Shiraz. Materials and Methods: Two MLVA (covering VNTR loci of 5, 9, 17 and 19) and MLST (comprising dnaA, gltX, gyrB, C, tufA genes) genotyping systems plus nucleotide structure analysis of P80 gene, was conducted. Results: The shared MLVA pattern represented by the three strains differed to that of the Mag PG2 laboratory strain, only at locus VNTR19 where the PG2 genome hold a 3 bp longer stretch. In MLST analysis, at dnaA, gltX, gyrB, metS and tufA loci, the three strains displayed alleles 1, 21, 2, 2 and 1, respectively. At, gltX locus a new allele (21) was detected where a new sequence type (ST33) was identified. Besides, the trio strains hold an identical nucleotide structure in their ma-mp81 gene. Conclusion: In explanation, lack of efficient disease control measures, has possibly contributed in evolution of a clone or a few clones that gradually overwhelmed the population over the time. Besides, the similarity between the Iranian and the PG2 strains, might be due to homoplasy or farming exercises such as animal importation. Inclusion of further local isolates in next studies will help to assess these assumptions.

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Serological prevalence of contagious bovine pleuropneumonia in agro-pastoral areas of Nigeria

Suleiman

Bellò

Dzikwi

et al. 2015

Trop Anim Health Prod

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CBPP is endemic to agro-pastoral areas, and it is doubtful if the current control strategies are making real impact in reducing production losses. Although eradication is more likely to be achieved through regional approaches, enhanced vaccination coverage supported with targeted surveillance and a trace back system based on cattle trade and movement records will sustain effective control of the disease in the Nigerian cattle population.

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Variable Number Tandem Repeat (VNTR) analysis reveals genetic diversity within Mycoplasma mycoides mycoides Small Colony isolates from Nigeria

Cited by 3 publications

References 3 publications

The Origin of the ‘Mycoplasma mycoides Cluster’ Coincides with Domestication of Ruminants

The Origin of the ‘Mycoplasma mycoides Cluster’ Coincides with Domestication of Ruminants

Homogeneity of Mycoplasma agalctiae vaccine strains in an agalaxy- high-burden environment

Serological prevalence of contagious bovine pleuropneumonia in agro-pastoral areas of Nigeria

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