Variable Expression of Albinism Within a Single Kindred

Clinical and Oculomotor Characteristics of Albinism Compared toFRMD7Associated Infantile Nystagmus

“…Other studies have also reported the presence of clinically detectable stereopsis in subjects with albinism. [32][33][34] The exact neural mechanism by which subjects with albinism demonstrate stereopsis is not known. Various studies suggest that the compensatory restructuring of corpus callosal projections could facilitate binocular disparate information in albino subjects.…”

Comparison of Clinical Findings in Pediatric Patients With Albinism and Different Amplitudes of Nystagmus

“…Other investigators have found a similar relationship between visual acuity and nystagmus in patients with albinism. 13,15,17,20 Summers et al 20 reported on 2 siblings with oculocutaneous albinism who demonstrated variable expression of vision and ocular alignment despite similar pigmentation. One sibling had normal vision with no nystagmus or strabismus, whereas the other had vision of 20/100 with nystagmus and a large-angle esotropia.…”

“…15,16 A clinical diagnosis of albinism can be made by the presence of iris transillumination and foveal hypoplasia, even in the absence of nystagmus. [13][14][15]17 In patients who display atypical clinical features, the diagno- Albinism is associated with a high prevalence of strabismic deviations, with reports ranging from 27 to 53%. 1,12,15,[17][18][19] Some patients with strabismus prefer to use one eye for fixation, and others will alternate fixation.…”