Variability of thujone content in essential oil due to plant development and organs from Artemisia absinthium L. and Salvia officinalis L.

Nguyen, Huong Thi Thu; Radácsi, Péter; Rajhárt, Péter; Németh, É.

doi:10.5073/jabfq.2019.092.014

Cited by 2 publications

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“…The content of thujones in the EO of A. absinthium can vary within a wide range. On this basis, thujone and sabinyl acetate EOs of A. absinthium were distinguished [ 22 ]. Thujone-containing and thujone-free forms are also characteristic of other wormwood species (e.g., A. campestris [ 23 ], A. molinieri [ 24 ]).…”

Section: Resultsmentioning

confidence: 99%

Chemical Diversity of Artemisia rutifolia Essential Oil, Antimicrobial and Antiradical Activity

Dylenova

Жигжитжапова

Emelyanova

et al. 2023

Plants

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This paper presents the results of the study of the composition of the essential oil (EO) of Artemisia rutifolia by the GC/MS method as well as its antimicrobial and antiradical activities. According to the PCA-analysis, these EOs can be conditionally divided into “Tajik” and “Buryat-Mongol” chemotypes. The first chemotype is characterized by the prevalence of α- and β-thujone, and the second chemotype by the prevalence of 4-phenyl-2-butanone, camphor. The greatest antimicrobial activity of A. rutifolia EO was observed against Gram-positive bacteria and fungi. The EO showed high antiradical activity with an IC50 value of 17.55 μL/mL. The presented first data on the composition and activity of the EO of A. rutifolia of the Russian flora indicate the prospects of the species as a raw material for the pharmaceutical and cosmetic industry.

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Section: Resultsmentioning

confidence: 99%

Chemical Diversity of Artemisia rutifolia Essential Oil, Antimicrobial and Antiradical Activity

Dylenova

Жигжитжапова

Emelyanova

et al. 2023

Plants

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Thujone, a widely debated volatile compound: What do we know about it?

Németh

Nguyen

2020

Phytochem Rev

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Thujone is a volatile monoterpene ketone of plant origin which is produced by several plants that are frequently used for flavoring foods and beverages. The use of thujone and thujone-containing plant parts for human consumption is currently regulated by the European Parliament and Council and the European Medicines Agency. The best known neurotoxic effects are connected to the GABA-gated chloride channel, where a-thujone is a modulator roughly two to three times as potent as the b isomer. Based primarily on in vitro experiments, genotoxicity and carcinogenic properties of thujones have also been detected in parallel with antimutagenic and immune-modulatory effects. Some of the controversial effects seem to be strongly dose-dependent. Data on antidiabetic and antimicrobial activities of thujones may show new ways to use them. This review also describes the main steps of the biosynthetic route of thujones and their occurrence in the plant kingdom. The accumulation of these compounds seems to be more abundant in some plant families (e.g. Asteraceae or Cupressaceae) than in others. Four species (Artemisia absinthium, Salvia

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Variability of thujone content in essential oil due to plant development and organs from Artemisia absinthium L. and Salvia officinalis L.

Cited by 2 publications

References 0 publications

Chemical Diversity of Artemisia rutifolia Essential Oil, Antimicrobial and Antiradical Activity

Chemical Diversity of Artemisia rutifolia Essential Oil, Antimicrobial and Antiradical Activity

Thujone, a widely debated volatile compound: What do we know about it?

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