Variability of Pasteurella multocida isolated from Icelandic sheep and detection of the toxA gene

Einarsdottir, Thorbjorg; Gunnarsson, Eggert; Sigurðardóttir, Ólöf; Jörundsson, Einar; Friðriksdóttir, Vala; Thorarinsdottir, Gudridur E.; Hjartardottir, Sigridur

doi:10.1099/jmm.0.000306

Journal of Medical Microbiology

2016

DOI: 10.1099/jmm.0.000306

|View full text |Cite

Variability of Pasteurella multocida isolated from Icelandic sheep and detection of the toxA gene

Thorbjorg Einarsdottir

Eggert Gunnarsson

Ólöf Sigurðardóttir

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2017

2021

Publication Types

Select...

Article7

Relationship

Self Cite0

Independent7

Authors

Journals

Cited by 8 publications

(2 citation statements)

References 45 publications

(49 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A recent study showed that isolates of ovine origin were highly diverse with respect to capsular types and MLST data as compared to abattoir isolates (Einarsdottir et al 2016). All the abattoir isolates belonged to capsular type D, whereas clinical isolates showed capsular types such as A, D or F (Einarsdottir et al 2016).…”

mentioning

confidence: 99%

Genetic diversity of Pasteurella multocida isolates of Indian origin

MISHRA¹,

Thomas

Kumar

et al. 2021

Indian J of Anim Sci

View full text Add to dashboard Cite

In the current study, correlation among specific capsular types, sequence types and specific hosts were observed. Study proves high diversity with respect to small ruminant isolates belonging to capsular type A. Higher sharing of sequence types among small ruminant, porcine and avian hosts indicate the close association of these isolates getting adapted for diverse host species. The study also shows that CC229, mostly from small ruminant hosts, was genetically related to HS-specific ST122 indicating recent diversification and possibly, similar genotype and pathogenesis.

show abstract

mentioning

confidence: 99%

Genetic diversity of Pasteurella multocida isolates of Indian origin

MISHRA¹,

Thomas

Kumar

et al. 2021

Indian J of Anim Sci

View full text Add to dashboard Cite

show abstract

“…Certain porcine strains of P. multocida responsible for atrophic rhinitis produce a mitogenic toxin (PMT) that is encoded by the toxA gene; notably, toxA is associated with a lysogenic Siphoviridae-type bacteriophage [36]. However, toxA has also more recently been identified in ovine P. multocida isolates [17,37,38], suggesting a role for bacteriophages in the horizontal transfer of toxA from porcine to ovine strains.…”

mentioning

confidence: 99%

Diversity and characterization of temperate bacteriophages induced in Pasteurella multocida from different host species

Abdulrahman

Davies

2021

BMC Microbiol

View full text Add to dashboard Cite

Background Bacteriophages play important roles in the evolution of bacteria and in the emergence of new pathogenic strains by mediating the horizontal transfer of virulence genes. Pasteurella multocida is responsible for different disease syndromes in a wide range of domesticated animal species. However, very little is known about the influence of bacteriophages on disease pathogenesis in this species. Results Temperate bacteriophage diversity was assessed in 47 P. multocida isolates of avian (9), bovine (8), ovine (10) and porcine (20) origin. Induction of phage particles with mitomycin C identified a diverse range of morphological types representing both Siphoviridae and Myoviridae family-types in 29 isolates. Phage of both morphological types were identified in three isolates indicating that a single bacterial host may harbour multiple prophages. DNA was isolated from bacteriophages recovered from 18 P. multocida isolates and its characterization by restriction endonuclease (RE) analysis identified 10 different RE types. Phage of identical RE types were identified in certain closely-related strains but phage having different RE types were present in other closely-related isolates suggesting possible recent acquisition. The host range of the induced phage particles was explored using plaque assay but only 11 (38%) phage lysates produced signs of infection in a panel of indicator strains comprising all 47 isolates. Notably, the majority (9/11) of phage lysates which caused infection originated from two groups of phylogenetically unrelated ovine and porcine strains that uniquely possessed the toxA gene. Conclusions Pasteurella multocida possesses a wide range of Siphoviridae- and Myoviridae-type bacteriophages which likely play key roles in the evolution and virulence of this pathogen.

show abstract

Potential DNA Vaccine for Haemorrhagic Septiceamia Disease

et al. 2020

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Variability of Pasteurella multocida isolated from Icelandic sheep and detection of the toxA gene

Cited by 8 publications

References 45 publications

Genetic diversity of Pasteurella multocida isolates of Indian origin

Genetic diversity of Pasteurella multocida isolates of Indian origin

Diversity and characterization of temperate bacteriophages induced in Pasteurella multocida from different host species

Potential DNA Vaccine for Haemorrhagic Septiceamia Disease

Contact Info

Product

Resources

About