Variability of area measurements obtained with different intravascular ultrasound catheter systems: impact on clinical trials and a method for accurate calibration

A nonimaging catheter for measurement of coronary artery lumen area

“…One of the primary objectives of this human pilot study was to define an acceptable level of accuracy for the LR System in comparison with IVUS. IVUS has been shown to have error depending on different catheters or systems used in phantoms [5]. Additionally, it has been shown that there is significant inter‐ and intra‐operator variability in interpretations of IVUS images [2, 3].…”

“…The objective of this pilot study was to establish the expected level of agreement between LR with IVUS (primarily) and QCA (secondary). Based on the animal studies and an IVUS study [5] showing that the largest error in phantom can reach 13% as compared to known diameter, we hypothesized a primary endpoint of the pilot study at 13% between LR and IVUS. The LR catheter was compared to both IVUS and quantitative coronary angiography (QCA) to assess accuracy and duplicate measurements were made to assess reproducibility of LR.…”

Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease

“…The accuracy and reproducibility of this method have been reported previously. 2,13 calculation of end points…”

Impacto dos stents e do sirolimus por via oral na vasomotilidade coronariana dependente e independente do endotelio

“…Atlantis SR TM Pro 40 MHz or Ultra Cross 30 MHz (Boston Scientific Corp, Natick, MA) catheters were used. To correct variability resulting from the use of various catheters, calibration equations were applied 19 . Offline analysis to determine cross-sectional areas and derived volumes was performed with appropriate software (QIVA, Pie Medical BV, Maastricht, The Netherlands).…”