effectively promote the expression of vascular endothelial growth factor (VEGF) in fibroblasts, and promote angiogenesis in vivo and in vitro [4] ; iii) ions and degradation products released from BGs can activate and up-regulate gene expression in bone progenitor cells, resulting in rapid bone regeneration and a higher rate of bone formation compared with other inorganic ceramics such as hydroxyapatite (HA), ttitanium dioxide, aluminium oxide. [5] In this paper, we review a series of breakthroughs and progresses in the application of BG, and discuss the future prospects of BG in bone regeneration, with the hope to provide a reference for further research on BGs.