Vancomycin-induced eosinophilic peritonitis

Abstract

A 37-year-old woman developed EP after receiving vancomycin intraperitoneally. The infection resolved after discontinuation of vancomycin.

Cefoperazone and sulbactam-related eosinophilic peritonitis: a case report and literature review

“…Moreover, vancomycin-related EP was reported twice in the literature. 16,17 All of these three patients were women. They all experienced bacterial peritonitis right before EP, and each of these three patients had a positive Staphylococcus culture in three of the four episodes, which suggests that prodromic infection plays an important role in EP pathogenesis.…”

“…They all experienced bacterial peritonitis right before EP, and each of these three patients had a positive Staphylococcus culture in three of the four episodes, which suggests that prodromic infection plays an important role in EP pathogenesis. EP can present in various forms such as from Rosner et al.’s case, 16 which described a patient who was previously asymptomatic, to Deweese et al.’s case, 17 in which the patient developed severe hypotension that was supported by vasopressors. Fortunately, all of these patients achieved remission after stopping the suspected antibiotic use.…”

“…Three original case reports of antibiotic-related EP in the literature were identified. [15][16][17] (Table 1) Piraino et al 15 described a series of patients with EP, four of whom were thought to have EP secondary to antibiotic use, but only one woman had EP twice after the initiation phase (in the first 3 months) of dialysis. Moreover, vancomycin-related EP was reported twice in the literature.…”

Eosinophilic peritonitis induced by sucroferric oxyhydroxide

“…3,4 Several drugs also induced eosinophilic peritonitis in patients undergoing PD. 5 –7 DLST was reported to help diagnose eosinophilic peritonitis in patients undergoing PD. 8 All reported cases of drug-induced eosinophilic peritonitis in patients undergoing PD were completely resolved by stopping the offending drugs with/without administering anti-allergic agents.…”

When the color of peritoneal dialysis effluent can be used as a diagnostic tool

“…Peritoneal fluid eosinophilia can also be related to infection (fungal, 41,42 parasitic, 43 tubercular 44 ), and appropriate tests must be performed to rule out these diagnoses in patients at risk. An allergic mechanism has been advanced to explain some cases of eosinophilic peritonitis following intraperitoneal injection of vancomycin 45,46 and streptokinase. 47 A turbid appearance of the dialysate can also be the consequence of an accumulation of neoplastic or abnormal cells.…”