“…For the dose-response study, 0, 0.1, 0.5, 1, 2, or 4 mg/kg V 2 O 5 was aspirated, and mice were euthanized on study d 14 (nϭ6 -8 mice/dose). For kinetic studies, 4 mg/kg V 2 O 5 was aspirated and mice were euthanized on study d 1,2,4,6,8,10,12,14,21,28,56,84, and 112 (nϭ4 -8/group). BXD RI strains were aspirated with 4 mg/kg V 2 O 5 or PBS on study d 0 and 7 and euthanized on study d 14 (nϭ4 -8/group).…”