Vanadium in Cancer Prevention

Das, Subhadeep; Chatterjee, Mary; Janarthan, M; Ramachandran, Hari K.; Chatterjee, Mainak

doi:10.1007/978-94-007-0913-3_8

Cited by 7 publications

(9 citation statements)

References 103 publications

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“…Vanadium exposure has been related with cytokine production (Dye et al, 1999), inflammatory changes in the upper and lower respiratory tracts (Pierce et al, 1996;Cohen et al, 2010) and lung tumours (Assem and Levy, 2012). However, other authors have suggested that V may mediate the inhibition of different forms of cancer (Das et al, 2012). Therefore, the use of V as a potential insulin-mimetic agent is subject to evaluation of the toxicity associated with its inflammatory effects.…”

Section: Introductionmentioning

confidence: 98%

Exposure to bis(maltolato)oxovanadium(IV) increases levels of hepcidin mRNA and impairs the homeostasis of iron but not that of manganese

Sánchez-González

Rivas-García

López-Chaves

et al. 2014

Food and Chemical Toxicology

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Section: Introductionmentioning

confidence: 98%

Exposure to bis(maltolato)oxovanadium(IV) increases levels of hepcidin mRNA and impairs the homeostasis of iron but not that of manganese

Sánchez-González

Rivas-García

López-Chaves

et al. 2014

Food and Chemical Toxicology

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“…The main food sources of V are rice, oats, buckwheat, wheat, barley, soy, beans, peas, potatoes, mushrooms, radishes, spinach, lettuce, parsley, olives, black pepper, dill weed, mussels, crabs, beer, wine, and artificially sweetened drinks [64,65,70,77]. With its physiological duality, V is essential in trace amounts (<0.0026 mg/L(kg) and toxic in excess (> 0.051 mg/L(kg) [78]. The mean V content in the diet was reported to be 0.032 mg/kg (range 0.019-0.050 mg/kg).…”

Section: Resultsmentioning

confidence: 99%

Vanadium Content of the Normal Human Prostate Gland: A Systematic Review

Zaichick¹

2021

Arch. Pharm. Pract

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Human prostate gland is subject to various disorders. The etiology and pathogenesis of these diseases are not still well comprehended. Furthermore, despite technological developments, the differential diagnosis of prostate disorders has become progressively more intricate and argumentative. It is proposed that the vanadium (V) extent in prostatic tissue has a significant role in prostatic carcinogenesis and its measurement can be helpful as a cancer biomarker. These suggestions promoted more detailed studies of the V content in the prostatic tissue of healthy subjects. By systematic analysis of the published data for V content, this study analyzed the prostatic tissue of "normal" glands. This evaluation reviewed 2127 studies, all of which were published in the years from 1921 to 2020, and was located by searching the databases PubMed, Scopus, ELSEVIER-EMBASE, Cochrane Library, and the Web of Science. The articles were analyzed and "Median of Means" and "Range of Means" were used to investigate the heterogeneity of the measured V content in prostates of apparently healthy men. The objective analysis was performed on data from the 17 studies, which included 664 subjects. It was found that the range of means of prostatic V content reported in the literature for "normal" gland differs widely from <0.010 mg/kg to 7.0 mg/kg with a median of means <0.034 mg/kg on a wet mass basis. Because of the small sample size and high data heterogeneity, we recommend that other primary studies are performed.

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“…With its physiological duality, vanadium is essential in trace amounts (0.05 µM) and toxic in excess (>10 µM) [28,29] (Fig. 5).…”

Section: Summarizing Note With Certain Aspects Of Essentiality Of V Omentioning

confidence: 99%

“…Furthermore, vanadium has also been recognized as essential for proper growth and development of certain animals [29,35]. The first suggestion about the essentiality of V for animals appeared in 1949, i.e.…”

Section: <Figure 6>mentioning

confidence: 99%