Vanadium Compounds as Insulin Mimics

51V NMR Chemical Shifts Calculated from QM/MM Models of Peroxo Forms of Vanadium Haloperoxidases

“…2 Vanadate is an essential prosthetic group of some isolated haloperoxidase enzymes. 3,4,5,6 Two such important proteins within this family are vanadium containing chloroperoxidase (VCPO) and vanadium containing bromoperoxidase (VBPO).…”

A novel VIVO–pyrimidinone complex: synthesis, solution speciation and human serum protein binding

“…Yield: 76%. 1 13 mmol), and ethanol (0.2 mL) were dissolved in dry THF (100 mL). NaH (2.34 g, 60% in oil, 58.5 mmol) was added and the mixture was stirred at room temperature for 48 h. THF was removed under vacuum, and the residue was dissolved in ethanol (100 mL), followed by addition of sodium ethoxide (3.75 g, 55.1 mmol) and acetamidine hydrochloride (5.21 g, 5.11 mmol).…”

“…Yield: 58.8%. 1 dbcpe and KOH (0.666 g; 11.8 mmol) were dissolved in methanol (50 mL) and stirred at room temperature. After 6 h the hydrolysis was complete, and a fine yellow-white precipitate had formed.…”

ESI–IT–MS n and DFT calculation for electron affinities of bimetallic oxovanadium complexes

“…These complexes are potentially useful as orally available treatments for diabetes mellitus and are used as catalysts in various oxidation reactions [1][2][3][4][5][6][7][8][9]. Structural characterization of the bimetallic oxovanadium complexes should be a key to the further development of their functions.…”