Abstract:Valvulopathies are among the most common cardiovascular diseases, significantly
increasing morbidity and mortality. While many valvular heart diseases are
acquired later in life, an important genetic component has been described,
particularly in mitral valve prolapse and bicuspid aortic valve. These conditions
can arise secondary to genetic syndromes such as Marfan disease (associated with
mitral valve prolapse) or Turner syndrome (linked to the bicuspid aortic valve)
or may manifest in a non-syndromic f… Show more
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