Valvular heart diseases in immigrants and Swedish-born individuals: a national cohort study

Wändell, Per; Li, Xinjun; Carlsson, Axel C.; Sundquist, Jan; Sundquist, Kristina

doi:10.1080/14017431.2022.2095014

Cited by 2 publications

References 21 publications

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Heart failure in first‐ and second‐generation immigrants aged 18–54 years in Sweden: A national study

Wändell,

Li,

Carlsson

et al. 2024

ESC Heart Failure

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PurposeWe aimed at analysing the risk of congestive heart failure (CHF) among first‐ and second‐generation immigrants in younger age groups.MethodsAll individuals aged 18–54 years, n = 3 973 454 in the first‐generation study and n = 3 817 560 in the second‐generation study, were included. CHF was defined as at least one registered diagnosis in the National Patient Register between 1 January 1998 and 31 December 2018. Cox regression analysis was used to estimate the relative risk [hazard ratios (HRs) with 99% confidence intervals (CIs)] of incident CHF with adjustments for age, co‐morbidities and socio‐demographics.ResultsIn the first‐generation study, a total of 85 719 cases of CHF were registered, 54 369 men and 31 350 women, where fully adjusted models showed HRs for all foreign‐born men of 1.12 (99% CI 1.06–1.17) and for women of 0.99 (0.92–1.05). Groups with higher risk included men from Eastern Europe, Central Europe, Africa and Asia and women from Africa and Asia, and a lower risk was found among Latin American women. In the second‐generation study, a total of 88 999 cases of CHF were registered, 58 403 men and 30 596 women, where fully adjusted models showed HRs for second‐generation men of 1.04 (0.99–1.09) and women of 0.97 (0.90–1.04).ConclusionsThe higher risk in some foreign‐born groups needs to be paid attention to in clinical practice. The fact that almost all increased risks were attenuated and absent in second‐generation immigrants suggests that lifestyle and environmental factors are more important than genetic differences in the risk of CHF.

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Heart failure in first‐ and second‐generation immigrants aged 18–54 years in Sweden: A national study

Wändell,

Li,

Carlsson

et al. 2024

ESC Heart Failure

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Surgical intervention for Mitral Stenosis: Temporal changes in patient characteristics, incidence, and mortality: a Danish nationwide cohort study

Due,

Petersen,

Meulengracht

et al. 2023

Preprint

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Aims: To examine temporal changes in patient characteristics, incidence rate of surgery, and three-year mortality rate for patients undergoing surgery for mitral valve stenosis in Denmark (2001-2021).. Methods and results: Utilizing Danish nationwide registries, we identified all adult patients undergoing first-time MS-intervention (2001-2021). Temporal changes across calendar periods were investigated (2001-2005, 2006-2010, 2011-2015, and 2016-2021). Using Kaplan-Meier estimates, we computed temporal changes in three-year all-cause mortality across calendar periods. With multivariable Cox regression analysis, we assessed adjusted rates of mortality. We included 256 patients (median age 60.3 years, 31.3% males). A decrease in the burden of chronic heart failure was identified (2001-2005:54%, and 2016-2021:20%, p-value<0.001), while the burden of atrial fibrillation seemed stable around 1 in 2. A decrease in rate of surgery was observed: 3.3 cases/million person-years (2001-2005), and 2.2 (2016-2021). The in-hospital mortality was 8.6% and the three-year mortality after discharge was 9.0%. We found no difference over calendar periods in crude estimates or adjusted analysis. Conclusion: From nationwide data (2001-2021), we identified the incidence of surgery, decreased significantly within the past 20 years while all-cause mortality remained stable. The burden of heart failure decreased while the burden of atrial fibrillation remained stable.

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Valvular heart diseases in immigrants and Swedish-born individuals: a national cohort study

Cited by 2 publications

References 21 publications

Heart failure in first‐ and second‐generation immigrants aged 18–54 years in Sweden: A national study

Heart failure in first‐ and second‐generation immigrants aged 18–54 years in Sweden: A national study

Surgical intervention for Mitral Stenosis: Temporal changes in patient characteristics, incidence, and mortality: a Danish nationwide cohort study

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