Values as determinant of meaning among patients with psychiatric disorders in the perspective of recovery

Huguelet, Philippe; Guillaume, Sébastien; Vidal, Sonia; Mohr, Sylvia; Courtet, Philippe; Villain, Lucile; Girod, Chloé; Hasler, Roland; Prada, Paco; Olié, Émilie; Perroud, Nader

doi:10.1038/srep27617

Cited by 27 publications

(19 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…epigenetic modifications, explain a part of the increased risk of depression of patients with child maltreatment history (Labonte et al, 2012;Radtke et al, 2015;Teicher et al, 2012;Weder et al, 2014), suggesting a direct effect of maltreatment on psychopathologic variables as depression. Meanwhile, in our previous research, we found that internalized symptoms (depression, hopelessness, low self-esteem) was associated with lower meaning in life (Huguelet et al, 2016). Hence, we tested a model in which the effect of child maltreatment was mediated by psychological symptoms.…”

Section: Introductionmentioning

confidence: 80%

“…This study showed that suffering from a chronic mental condition was associated with reduced meaning in life and impaired values. Moreover, level of depression and hopelessness was associated with lower meaning in life (Huguelet et al, 2016). In this perspective, one might think that it exists an association between child maltreatment and meaning in life, appearing in a multitude of persistent psychiatric disorders, and limiting the potential of recovery in these subjects.…”

Section: Introductionmentioning

confidence: 99%

“…Meaning in life has scarcely been studied in populations with psychiatric disorders. Our group has recently specifically focused on the determinants of meaning among subjects facing severe mental disorders, and developed a general framework linking one's biopsycho-social context with values and meaning (Huguelet, 2013;Huguelet et al, 2016). This study showed that suffering from a chronic mental condition was associated with reduced meaning in life and impaired values.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Impact of child maltreatment on meaning in life in psychiatric patients

Weibel

Vidal

Olié

et al. 2017

Psychiatry Research

Self Cite

View full text Add to dashboard Cite

Child maltreatment (CM) worsens prognosis and quality of life in several psychiatric conditions. Meaning in life is a construct which relates to the sense of purpose that one can perceive in life, and is a key aspect of recovery in psychiatric patients. The lasting impact of CM on meaning in life and its mediating variables have not been studied in patients with chronic persistent psychiatric conditions. One hundred and sixty-six patients with bipolar disorder (N=35), psychotic disorder (N=73), anorexia nervosa (N=30) or borderline personality disorder (N=28) were assessed for meaning in life (revised version of the Life Regard Index (LRI-R)), for CM (Childhood Trauma Questionnaire (CTQ)) and for internalized/externalized psychopathology. CM was associated with a lower LRI score. Structural Equation Modeling showed that internalized psychopathology (depression, hopelessness and low self-esteem) was the main mediator of the impact of CM on meaning in life. The direct effect of CM on meaning in life was not significant. Having suffered from negligence or abuse during childhood is associated with lower meaning in life in adults with persistent and pervasive psychiatric disorders. Treating depressive symptoms and improving self-esteem may improve meaning in life in patients with severe mental disorders who were affected by CM.

show abstract

Section: Introductionmentioning

confidence: 80%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Impact of child maltreatment on meaning in life in psychiatric patients

Weibel

Vidal

Olié

et al. 2017

Psychiatry Research

Self Cite

View full text Add to dashboard Cite

show abstract

“…In mental health, recovery is understood as a process of personal growth that involves hope, a sense of personal identity, leading a life of meaning and assuming responsibilities 38. The loss of identity and social roles is observed from the very first psychotic episodes 26.…”

Section: Discussionmentioning

confidence: 99%

‘Being normal’ and self-identity: the experience of volunteering in individuals with severe mental disorders—a qualitative study

Pérez-Corrales

Pérez-de-Heredia-Torres

Martínez-Piedrola

et al. 2019

BMJ Open

View full text Add to dashboard Cite

ObjectiveThis study sought to explore the views and experiences of a group of people with severe mental disorders (SMDs) who performed volunteer services.DesignA qualitative phenomenological study.SettingCommunity public mental health services of the Community of Madrid and the province of Barcelona (Spain).ParticipantsPurposive sampling techniques were used between September 2016 and April 2017. The inclusion criteria were: individuals aged 18–65 years who participated in volunteer activities during the performance of this study, based on the regulations of volunteer services in Spain and the community of Madrid; a diagnosis of non-organic psychotic disorder (F20.x, F21, F22, F24, F25, F28, F29, F31.x, F32.3 and F33) according to the International Classification of Diseases, 10th Revision; an evolution of ≥2 years; and a moderate to severe dysfunction of global functioning with scores ≤70 in the Global Assessment of Functioning Scale. Ultimately, 23 people with SMD participated in the study with a mean age of 47 years (SD 8.23).MethodsData were collected through in-depth interviews and researcher field notes. A thematic analysis was performed following appropriate guidelines for qualitative research.ResultsTwo main themes emerged to describe the experience of participating in volunteer activities: (1) rebuilding self-identity, based on the participant’s experience of volunteering, of acquiring a new role and a new perceived identity that made them feel valued and respected; and (2) being a so-called normal person with a ‘normal’ life, based on recovering a sense of normality, unmarked by the illness, thanks to daily responsibilities and occupations.ConclusionsQualitative research offers insight into the way people with SMD experience volunteering and may help to improve understanding of the underlying motivations that drive these individuals. These findings may be applied to improve guidance during their process of recovery and subsequent inclusion into society.

show abstract

“…As in the previous analysis, a weighted stepwise linear regression was performed between the z-values of natural logarithm of binding (in this case V T / f P ) for each region and the z-values of three predictors: somatic, motoric and psychic anxiety component scores. As the scales for the predictors were different, we performed the commonly used (Huguelet et al, 2016) z-value standardization in order to ensure that the contributions of the variables to the analysis will be same. The natural logarithm of the outcome measure was applied to improve model fitting as the residuals become closer to normal distribution when this transformation is applied.…”

Section: Methodsmentioning

confidence: 99%

A positron emission tomography study of the serotonergic system in relation to anxiety in depression

İşcan

Rakesh

Rossano

et al. 2017

European Neuropsychopharmacology

View full text Add to dashboard Cite

Symptoms of anxiety are highly comorbid with major depressive disorder (MDD) and are known to alter the course of the disease. To help elucidate the biological underpinnings of these prevalent disorders, we previously examined the relationship between components of anxiety (somatic, psychic and motoric) and serotonin 1A receptor (5-HT1A) binding in MDD and found that higher psychic and lower somatic anxiety was associated with greater 5-HT1A binding. In this work, we sought to examine the correlation between these anxiety symptom dimensions and 5-HTT. Positron emission tomography with [11C]-3-amino-4-(3-dimethylamino-methylphenylsulfanyl)-benzonitrile ([11C]DASB) and a metabolite-corrected arterial input function were used to estimate regional 5-HTT binding in 55 subjects with MDD and anxiety symptoms. Somatic anxiety was negatively correlated with 5-HTT binding in the thalamus (β=−.33, p=.025), amygdala (β=−.31, p=.007) and midbrain (β=−.72, p<.001). Psychic anxiety was positively correlated with 5-HTT binding in midbrain only (β=.46, p=.0025). To relate to our previous study, correlation between 5-HT1A and 5-HTT binding was examined, and none was found. We also examined how much of the variance in anxiety symptom dimensions could be explained by both 5-HTT and 5-HT1A. The developed model was able to explain 68% (p<.001), 38% (p=.012) and 32% (p=.038) of the total variance in somatic, psychic, and motoric anxiety, respectively. Results indicate the tight coupling between the serotonergic system and anxiety components, which may be confounded when using aggregate anxiety measures. Uncovering serotonin’s role in anxiety and depression in this way may give way to a new generation of therapeutics and treatment strategies.

show abstract

Values as determinant of meaning among patients with psychiatric disorders in the perspective of recovery

Cited by 27 publications

References 32 publications

Impact of child maltreatment on meaning in life in psychiatric patients

Impact of child maltreatment on meaning in life in psychiatric patients

‘Being normal’ and self-identity: the experience of volunteering in individuals with severe mental disorders—a qualitative study

A positron emission tomography study of the serotonergic system in relation to anxiety in depression

Contact Info

Product

Resources

About