Value of Virtual Colonoscopy with 64 Row CT in Evaluation of Colorectal Cancer

Abstract

SummaryBackgroundVirtual colonoscopy (VC) enables three-dimensional view of walls and internal lumen of the colon as a result of reconstruction of multislice CT images. The role of VC in diagnosis of the colon abnormalities systematically increases, and in many medical centers all over the world is carried out as a screening test of patients with high risk of colorectal cancer.Material/MethodsWe analyzed results of virtual colonoscopy of 360 patients with clinical suspicion of colorectal cancer. Sensitivity and specificity of CT colonoscopy for detection of colon cancers and polyps were assessed.ResultsResults of our research have shown high diagnostic efficiency of CT colonoscopy in detection of focal lesions in large intestine of 10 mm or more diameter. Sensitivity was 85.7%, specificity 89.2%.ConclusionsVirtual colonoscopy is noninvasive and well tolerated by patients imaging method, which permits for early detection of the large intestine lesions with specificity and sensitivity similar to classical colonoscopy in screening exams in patients suspected for colorectal cancer. Good preparation of the patients for the examination is very important for proper diagnosis and interpretation of this imaginge procedure.

Preoperative Serum MicroRNA-155 Expression Independently Predicts Postoperative Cognitive Dysfunction After Laparoscopic Surgery for Colon Cancer

“…Along with the development of diagnosis and treatment regimens, the survival rate of patients with CRC has significantly increased during the past few years. Multi-detector computed tomography (MDCT) and virtual colonoscopy with 64-row CT are both useful imaging methods for early detection of CRC and are tolerated well by patients [2,3]. The use of laparoscopic surgery for CRC is increasing rapidly, and some institutions regard laparoscopy as the standard procedure for surgical treatment of CRC.…”

Photodynamic diagnosis and photodynamic therapy of colorectal cancer in vitro and in vivo

“…6,8,16 Furthermore, classical colonoscopy specicity and sensitivity limitations also include the fact that it may detect lesions other than CRC polyps and is unable to discriminate a benign adenoma from an invasive carcinoma. [17][18][19]…”

Diagnostic value of computed tomography colonography (CTC) after incomplete optical colonoscopy

“…Apart from better diagnostic performance, CTC is also more tolerable and acceptable to patients and delivers a lower effective radiation dose than BE [42]. Indeed, the execution of CTC is easy, nearly painless, minimally invasive and well tolerated by patients who are generally more willing to undergo this procedure rather than repeat OC [4,43,44].…”

“…CTC examination process is standardized and consists of four consecutive steps: bowel cleansing, colon distention, CT protocol, and image analysis [2,4,11,43]. In order to obtain a CTC study of good quality it is essential to achieve a clean and well-distended colon.…”