Value of three‐dimensional speckle‐tracking imaging in detecting left ventricular systolic function in patients with dilated cardiomyopathy

Abstract

Objective To explore the value of three‐dimensional speckle‐tracking imaging (3DSTI) in detecting left ventricular systolic function in patients with dilated cardiomyopathy (DCM). Methods Totally 31 DCM patients were enrolled in this study. Left ventricular end‐systolic volume (LVESV), left ventricular end‐diastolic volume (LVEDV), and left ventricular ejection fraction (LVEF) were measured using the 3DSTI, two‐dimensional echocardiography (2DE), and magnetic resonance imaging (MRI). Left ventricular end‐diastolic mass (EDmass) and left ventricular end‐diastolic mass index (LVEDmass I) were also detected by 3DSTI and MRI. The differences in these measurements were analyzed and compared. Results The values of LVESV, LVEDV, and LVEF showed significantly positive correlations among 2DE group, 3DSTI group, and MRI group. The LVEF value showed significant difference among these three groups [(33.3 ± 11.1)%, (30.3 ± 10.6)%, and (26.2 ± 10.7)%; P = 0.04], whereas LVEDV and LVESV values were not significantly different (P &gt; 0.05; respectively). Inter‐group comparison showed the mean of LVEF was significantly lower in MRI group than in 2DE group (P = 0.031), whereas there was no significant difference between 2DE group and 3DSTI group and between 3DSTI group and MRI group (P &gt; 0.05; respectively). The EDmass and EDmassI detected by 3DSTI and MRI were (143.2 ± 40.2) g vs (190.0 ± 58.3) g and (83.2 ± 21.1) g/m2 vs (110.1 ± 29.7) g/m2 (P < 0.001; respectively). Conclusions The LVEF value detected by 3DSTI is closer to that detected by MRI in DCM patients.

Changes in left ventricular function induced by carboplatin combined with paclitaxel in patients with ovarian cancer identified using three‐dimensional spot tracking imaging technology

“…At present, MRI is considered the gold standard to detect LV systolic function. 9 In the present study, MRI and 3D-STI results were concordant regarding ESV, EDV, and LVEF, and both methods showed no significant change in ESV and EDV after chemotherapy.…”

“…Therefore, the abovementioned variables may be indicators of LV damage in patients treated with the chemotherapy regimen of carboplatin combined with paclitaxel. At present, MRI is considered the gold standard to detect LV systolic function 9 . In the present study, MRI and 3D‐STI results were concordant regarding ESV, EDV, and LVEF, and both methods showed no significant change in ESV and EDV after chemotherapy.…”

Changes of left ventricular function induced by carboplatin combined with paclitaxel in patients with ovarian cancer treated by three-dimensional speckle tracking imaging technology

“…Therefore, the above parameters can be used as an effective indicator of response to carboplatin combined with paclitaxel chemotherapy for LV damage. At present, MRI is regarded as the gold standard to detect LV systolic function [9] . 3D-STI was positively correlated with ESV, EDV and LVEF measured by MRI (P < 0.05), and there was no significant difference between the two methods in ESV and EDV results (P > 0.05), so 3D-STE is more suitable than MRI in clinical application.…”

Cardiomyopathies in China: A 2018–2019 state‐of‐the‐art review

“…Impairment of the global longitudinal strain, which provides an assessment of regional contractility, can distinguish patients with inflammation from those without. 28 Strain analyses based on a deformable registration algorithm can be a great tool for identifying DCM patients with varying degrees of mechanical dyssynchrony, which is associated with the prognosis of patients with DCM. Further, circumferential uniformity ratio estimate is the best parameter for differentiating DCM patients with normal QRS duration from patients with left bundle branch block (LBBB).…”