2018
DOI: 10.1007/s00392-018-1285-4
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Value of the CHA2DS2-VASc score and Fabry-specific score for predicting new-onset or recurrent stroke/TIA in Fabry disease patients without atrial fibrillation

Abstract: ObjectivesTo evaluate potential risk factors for stroke or transient ischemic attacks (TIA) and to test the feasibility and efficacy of a Fabry-specific stroke risk score in Fabry disease (FD) patients without atrial fibrillation (AF).BackgroundFD patients often experience cerebrovascular events (stroke/TIA) at young age.Methods159 genetically confirmed FD patients without AF (aged 40 ± 14 years, 42.1% male) were included, and risk factors for stroke/TIA events were determined. All patients were followed up ov… Show more

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Cited by 13 publications
(7 citation statements)
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“…Cardiac analyses were performed with a standardized protocol oriented toward guidelines and special on‐site experience. Analyses and classification of myocardial hypertrophy were conducted offline by a single experienced investigator with EchoPAC and TomTech …”
Section: Methodsmentioning
confidence: 99%
See 1 more Smart Citation
“…Cardiac analyses were performed with a standardized protocol oriented toward guidelines and special on‐site experience. Analyses and classification of myocardial hypertrophy were conducted offline by a single experienced investigator with EchoPAC and TomTech …”
Section: Methodsmentioning
confidence: 99%
“…Analyses and classification of myocardial hypertrophy were conducted offline by a single experienced investigator with EchoPAC and TomTech. 44,45 Statistical analysis Variables are expressed as the mean ± SD, or alternatively, as the median and IQR. Categorical variables are presented as the count and percentage.…”
Section: Echocardiographymentioning
confidence: 99%
“…The administration of any bradycardia‐inducing drugs should be done with extreme caution with regular ambulatory ECG monitoring ( Table 4 ). 69,90,271,273,279–281,283–294 …”
Section: Management Of Cardiac Complicationsmentioning
confidence: 99%
“…A new predicting score based on these risk factors was proposed to predict stroke/TIA in FD patients without atrial fibrillation. It remains to clarify if high-risk patients, according to this score, might benefit from antithrombotic therapy [ 212 ].…”
Section: Cardiac Treatment In Fdmentioning
confidence: 99%