“…An interesting side effect of the use of ion exchange resins is the production of an increased number of urinary casts by the increased acidity associated with the use of resins in the hydrogen or ammonium form (111). In cases with massive edema, the use of Southey-Leech tubes may be highly effective and harmless (112). The natural fluctuations in the course of nephrosis make the evaluation of therapy even more difficult.…”