Value of serum GGT level in the timing of diagnosis of choledochal cyst perforation

Zhang, Shuhao; Cai, Duote; Chen, Qingjiang; Zhang, Yuebin; Chen, Ken; Jiang, Y.; Luo, Wenjuan; Huang, Ze-Ning; Hu, Di; Gao, Zhigang

doi:10.3389/fped.2022.921853

Cited by 3 publications

(3 citation statements)

References 19 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(3) Patients with no history of previous abdominal surgery; (4) Con rmation of CC with perforation or cystic necrotic changes.…”

Section: Inclusion Criteriamentioning

confidence: 99%

“…CC with perforation is a rare condition 3 , and the mechanism of choledochal cyst perforation is not yet clear. The current understanding suggests that it is caused by the re ux of pancreatic enzymes, increased pressure in the bile duct due to protein blockage, and viral infection 4 . CC with perforation, as an acute abdomen, requires immediate surgical intervention.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A nomogram for predicting choledochal cyst with perforation

Zhang,

Wang,

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Choledochal cyst with perforation (CC with perforation) rarely occurs, early diagnosis and timely treatment plan are crucial for the treatment of CC with perforation. This study aims to forecast the occurrence of CC with perforation.Methods All 1111 patients were conducted, who underwent surgery for choledochal cyst at our hospital from January 2011 to October 2022. We conducted univariate and multivariate logistic regression analysis to screen for independent predictive factors for predicting CC with perforation, upon which established a nomogram. The predictive performance of the nomogram was evaluated using receiver operating characteristic (ROC) curves, calibration plots, and decision curve analysis (DCA) curves.Results The age of children with choledochal cyst perforation is mainly concentrated between 1 and 3 years old. Logistic regression analysis indicates that age, alanine aminotransferase, glutamyl transpeptidase, C-reactive protein, vomiting, jaundice, abdominal distension, and diarrhea are associated with predicting the occurrence of choledochal cyst perforation. ROC curves, calibration plots, and DCA curve analysis curves demonstrate that the nomogram has great discriminative ability and calibration, as well as significant clinical utility.Conclusion The age of CC with perforation is mainly concentrated between 1–3 years old. A nomogram for predicting the perforation of choledochal cyst was established.

show abstract

“…(3) Patients with no history of previous abdominal surgery; (4) Con rmation of CC with perforation or cystic necrotic changes.…”

Section: Inclusion Criteriamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A nomogram for predicting choledochal cyst with perforation

Zhang,

Wang,

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…CC with perforation is a rare condition [ 3 ], and the mechanism of choledochal cyst perforation is not yet clear. The current understanding suggests that it is caused by the reflux of pancreatic enzymes, increased pressure in the bile duct due to protein blockage, and viral infection [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

A nomogram for predicting choledochal cyst with perforation

Zhang,

Wang,

et al. 2024

Pediatr Surg Int

View full text Add to dashboard Cite

Background Choledochal cyst with perforation (CC with perforation) rarely occurs, early diagnosis and timely treatment plan are crucial for the treatment of CC with perforation. This study aims to forecast the occurrence of CC with perforation. Methods All 1111 patients were conducted, who underwent surgery for choledochal cyst at our hospital from January 2011 to October 2022. We conducted univariate and multivariate logistic regression analysis to screen for independent predictive factors for predicting CC with perforation, upon which established a nomogram. The predictive performance of the nomogram was evaluated using receiver operating characteristic (ROC) curves, calibration plots, and decision curve analysis (DCA) curves. Results The age of children with choledochal cyst perforation is mainly concentrated between 1 and 3 years old. Logistic regression analysis indicates that age, alanine aminotransferase, glutamyl transpeptidase, C-reactive protein, vomiting, jaundice, abdominal distension, and diarrhea are associated with predicting the occurrence of choledochal cyst perforation. ROC curves, calibration plots, and DCA curve analysis curves demonstrate that the nomogram has great discriminative ability and calibration, as well as significant clinical utility. Conclusion The age of CC with perforation is mainly concentrated between 1 and 3 years old. A nomogram for predicting the perforation of choledochal cyst was established.

show abstract