Value of Self‐Reportable Screening Criteria to Identify Asymptomatic Individuals in the General Population for UrogentialChlamydia trachomatisInfection Screening

Abstract

Submission of samples from the home allows screening for Chlamydia trachomatis without preceding professional assessment of clinical risk factors. Therefore, a validation of self-reportable information for use as selective screening criteria is needed. We asked a total of 1175 women and 1033 men who participated in an in-home sampling screening study to provide information on behavior and sociodemographic characteristics. In a multivariate model, selective screening criteria were developed on the basis of information from a random part of the tested population (development group), and the validity was assessed for the remaining part of the tested population (validation group). To find all infections, 95% of the subjects had to be screened, and screening 63% of them would have detected 86% of infections. Low predictive values were found when selective screening criteria from other studies were assessed. Selective screening by means of in-home sampling strategies among men and women aged 21-23 years cannot be recommended in the area studied.

Mycoplasma genitalium: prevalence and behavioural risk factors in the general population

“…This points to the possibility that condoms might be less protective against M genitalium infection than against other STIs such as C trachomatis. 29 We conclude that the prevalence of M genitalium infection in the general population is low. However, based on our results we also hypothesise that it will be possible in the future to define test algorithms based on behavioural risk factors to select individuals with a higher prevalence of infection.…”

Prediction of Costs, Effectiveness, and Disease Control of a Population-Based Program Using Home Sampling for Diagnosis of Urogenital Chlamydia trachomatis Infections

“…Continuous evaluation of the program is hence very important, and the more the infection prevalence declines, the more relevant it becomes to seek to identify subgroups of individuals having a higher risk of infection, e.g., by use of selective self-reportable screening criteria. 50 This study suggests that implementing home sampling for population-based screening and partner notification improves the control of C trachomatis infections and that the infection prevalence will fall significantly. Furthermore, the implementation of such a program may be cost-saving to society after 4 years.…”

Predictors identifying those at increased risk for STDs: a theory-guided review of empirical literature and clinical guidelines

“…25–29 These studies were omitted from the second stage of review. Studies rated as ‘marginal’ (24%), 7,30–46 ‘acceptable’ (41%) 47–77 and ‘commendable’ (28%) 4,78–…”