Value of Red Blood Cell Distribution Width on Emergency Department Admission in Patients With Venous Thrombosis

Lippi, Giuseppe; Buonocore, Ruggero; Cervellin, Gianfranco

doi:10.1016/j.amjcard.2015.11.024

Cited by 26 publications

(22 citation statements)

References 19 publications

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“…The intriguing association between RDW and outcomes of ACS adds further evidence about the clinical usefulness of investigating anisocytosis in health and disease. Enhanced RDW values have been found to be associated with death and complications in many other chronic and highly prevalent conditions such as cancer (26), diabetes (27), venous thromboembolism (28) and severe allergic reactions (29). Indeed, major derangements of many common biological pathways are known to occur in these conditions, which are mostly characterized by apoptosis, malnutrition, chronic inflammatory response and fibrosis.…”

Section: Discussionmentioning

confidence: 99%

Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome

et al. 2016

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“…Adding markers is highly desirable. In recent years, more and more attention is given to the role of inflammatory markers in different diagnosis . Few studies have been done about inflammatory factors in correlation to DVT and PE.…”

Section: Introductionmentioning

confidence: 99%

The role of neutrophil‐lymphocyte ratio, and mean platelet volume in detecting patients with acute venous thromboembolism

Farah

Nseir

Kagansky

et al. 2019

Clinical Laboratory Analysis

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Background: Acute venous thromboembolism (VTE) refers to deep venous thrombosis (DVT) of the extremities or pulmonary embolism (PE), or to both. Reliable imaging is not always available making a serologic diagnosis, or biomarker, highly desirable. Objective: This study aimed to examine the role of neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV) in detection patients with acute VTE. How to cite this article: Farah R, Nseir W, Kagansky D, Khamisy-farah R. The role of neutrophil-lymphocyte ratio, and mean platelet volume in detecting patients with acute venous thromboembolism.

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“…Depending on the hematological analyzer, the upper limit of the reference range of RDW-CV varies between 14.0% and 15.0%, with a reference value of 14.6% identified in many clinical trials, as reported elsewhere [7]. Recent evidence attests that the introduction of RDW in diagnostic algorithms may be useful in the initial evaluation of patients with a vast array of human disorders such as cardiovascular disease [8], venous thrombosis [9], cancer [10] and severe infections [11], but is also a powerful and independent predictor of clinical outcomes, including short- and long-term mortality [12]. …”

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confidence: 99%

Red blood cell distribution width in patients with limb, chest and head trauma

Lippi

Bovo

Buonocore

et al. 2017

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IntroductionThis study investigated the values of red blood cell distribution width (RDW), an emerging and independent predictor of morbidity and mortality, in patients with limb, chest and head trauma.Material and methodsThe study sample consisted of all patients who attended the emergency department (ED) of the University Hospital of Parma for limb, chest and head traumas requiring admission to hospital wards during the year 2014. The controls consisted of outpatients living in the same geographical area and undergoing routine laboratory testing for health check-up.ResultsThe final study sample consisted of 290 patients with limb (n = 97), chest (n = 49) or head (n = 144) trauma and 967 outpatients. Significantly increased RDW values at admission were observed in all trauma patients compared with controls. Although the frequency of increased RDW (> 14.6%) was higher in all trauma patients than in controls, a subanalysis revealed that increased RDW values were significantly more frequent in patients with head trauma than in controls, but not in those with limb or chest trauma. In multivariate analysis, a significant association was found between head trauma and hemoglobin (p < 0.001) or RDW (p = 0.005). Head trauma patients had a ~3-fold higher likelihood of increased RDW values than controls. The negative and positive predictive values of increased RDW for predicting the presence of head trauma were 0.90 (95% CI: 0.88–0.92) and 0.24 (95% CI: 0.19–0.30).ConclusionsThe results of this study highlight that RDW is increased in patients admitted to the ED with head trauma.

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Value of Red Blood Cell Distribution Width on Emergency Department Admission in Patients With Venous Thrombosis

Cited by 26 publications

References 19 publications

Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome

Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome

The role of neutrophil‐lymphocyte ratio, and mean platelet volume in detecting patients with acute venous thromboembolism

Red blood cell distribution width in patients with limb, chest and head trauma

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