Value of layer-specific speckle tracking echocardiography for early detection of myocardial injury caused by chemotherapy in breast cancer patients with cardiovascular risk

Ya, Tan; Wang, Lijun; Hu, Bo; Chen, Chuang; Jiang, Nan; Cao, Qingqiong; Lei, Jiarui; Guo, Ruiqiang

doi:10.1007/s10554-021-02367-0

Cited by 2 publications

(2 citation statements)

References 23 publications

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“…Chen et al (2022) [25] believed that 2D-STI ECG was more accurate and sensitive in monitoring the abnormalities of cardiac functions caused by ANTH therapy than routine ECG, which was consistent with the research nding that 2D-STI parameters were more superior to routine ECG parameters in predictive effectiveness. Tan et al (2022) [26] also con rmed that speci c speckle tracking ECG showed remarkable clinical application values in the early monitoring of toxicityrelated myocardial injury among patients with breast carcinoma after chemotherapy with epirubicin. However, there was no research into the application of routine ECG parameters combined with 2D-STI parameters in myocardial injury.…”

Section: Discussionmentioning

confidence: 99%

Monitoring Values of Routine Echocardiography and Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Song,

Ma,

Sun

et al. 2024

Preprint

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Objective This research was conducted to investigate the monitoring values of routine echocardiography (ECG) and two-dimensional speckle tracking imaging (2D-STI) in cardiotoxicity caused by the treatment of breast carcinoma with anthracyclines (ANTH). Methods 100 patients with breast carcinoma were selected and enrolled into normal group (n = 53 cases) and abnormal group (47 cases) according to whether ECG was abnormal. Routine ECG and 2D-STI were employed for the detection, ECG- and 2D-STI-related parameters were compared, receiver operating characteristic (ROC) curves were drawn, and the clinical application values of monitoring methods for two groups were assessed. Results Before chemotherapy, no remarkable statistical difference was detected in routine ECG and 2D-STI parameters between normal and abnormal groups (P > 0.05). After 6 cycles, E/V value of abnormal group was inferior to that of normal group ((0.93 ± 0.16) vs (1.33 ± 0.23). Besides, longitudinal peak strain (SRI) values of rear wall, front spacer, and rear spacer in abnormal group were inferior to those in normal group (P < 0.05). Routine ECG combined with 2D-STI had the best predictive effect followed by 2D-STI and routine ECG. Conclusion To sum up, 2D-STI was a new method for assessing myocardial lesions and possessed significant early clinical monitoring values in cardiotoxicity caused by chemotherapy after the treatment of breast carcinoma with ANTH. It had higher clinical application values than routine ECG.

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Section: Discussionmentioning

confidence: 99%

Monitoring Values of Routine Echocardiography and Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Song,

Ma,

Sun

et al. 2024

Preprint

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“…[32][33][34] In patients receiving cancer chemotherapy, GLS provides crucial information during chemotherapy drug titration and follow-up and helps estimate the extent of myocardial damage. 35,36 The GLS could provide management decision-making in valvular heart disease with normal EF and asymptomatic valvular heart disease. 37,38 GLS helps in the early detection of myocardial damage before the reduction in EF.…”

Section: Strain Analysismentioning

confidence: 99%

Evaluation of Systolic Function of Left Ventricle

Jha

2024

Journal of Acute Care

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The left ventricle (LV) is a complex structure, and understanding functional complexity is crucial while evaluating the systolic function. Systolic function is the predominant determinant of stroke volume and cardiac output and has substantial clinical implications. Internal dimension, volumes, and fractional shortening are routinely used in clinical practice to assess LV systolic function. Ejection fraction (EF) estimation using two-dimensional (2D) echocardiography is ubiquitous. However, the reliability of EF in prognostication and decision among patients with normal to mildly reduced EF is questionable. Therefore, other 2D or three-dimensional (3D) echocardiographic variables and strain measurements are continuously evolving to supplement and complement EF. However, we need to generate sufficient normative data in normal patients and those with various cardiac pathologies to validate and strengthen the clinical utility of strain.

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Value of layer-specific speckle tracking echocardiography for early detection of myocardial injury caused by chemotherapy in breast cancer patients with cardiovascular risk

Cited by 2 publications

References 23 publications

Monitoring Values of Routine Echocardiography and Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Monitoring Values of Routine Echocardiography and Two-dimensional Speckle Tracking Imaging in Cardiotoxicity Caused by Treatment of Breast Carcinoma with Anthracyclines

Evaluation of Systolic Function of Left Ventricle

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