Value of fructosamine measurement in pregnant women with abnormal glucose tolerance

Li, Kui; Yang, Huixia

doi:10.1097/00029330-200611020-00003

Cited by 18 publications

(13 citation statements)

References 17 publications

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“…Fructosamine is a preferred alternative because it can be obtained from a single random blood sample and does not require an OGTT [292]. However, fructosamine was insensitive for identifying GDM in early pregnancy [293] . Therefore, fructosamine may be a good biomarker to predict neonatal outcomes and maternal glycemia but additional studies are needed to establish suitable reference ranges [293][294][295][296][297].…”

Section: Fructosaminementioning

confidence: 99%

Review of methods for detecting glycemic disorders

Bergman

Abdul‐Ghani

Manco

et al. 2020

Diabetes Research and Clinical Practice

123

101

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Highlights A 1-hour plasma glucose (1-h PG) threshold >155 mg/dl (8.6 mmol/L) during an oral glucose tolerance test (OGTT) may be a suitable biomarker for identifying normal glucose tolerant (NGT) individuals at risk for future type 2 diabetes (T2D). A one-hour, non-fasting, 50g Glucose Challenge Test (GCT) performed during a routine health care visit has potential for practical screening of glucose disorders. The shape of the glucose curve reflects the cumulative effect of insulin sensitivity and response on glucose concentrations with prospective studies warranted to evaluate its prognostic utility. The continuous glucose monitor (CGM) has facilitated insight into the pathophysiology of prediabetes and phenotypes of T2D and holds promise for detecting glycemic disorders. Metabolomic profiling including amino acids, lipids, carbohydrates and other metabolites may be useful for early diagnosis of glycemic disorders. Non-classical markers for assessing glycemic disorders including fructosamine, glycated albumin, and 1,5-anhydroglucitol that evaluate shorter periods of glucose exposure than HbA1c have potential use as adjunctive tools.

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Section: Fructosaminementioning

confidence: 99%

Review of methods for detecting glycemic disorders

Bergman

Abdul‐Ghani

Manco

et al. 2020

Diabetes Research and Clinical Practice

123

101

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“…Glycated albumin and fructosamine (measuring total glycated serum proteins) provide a measure of glycemic status over the last 2-4 weeks and have been associated with the development of diabetes and microvascular complications in non-pregnant adults [15,16]. Although fructosamine and glycated albumin are unaffected by altered hemoglobin concentration, potential disadvantages to the use of fructosamine include the variability of albumin and protein concentration due to the dilutional effects of pregnancy so that fructosamine falls with advancing gestational age [17]. Glycated albumin, expressed as a proportion of total albumin concentrations, shows less variation with gestational age and iron deficiency [14].…”

Section: Discussionmentioning

confidence: 99%

Novel Biochemical Markers of Glycemia to Predict Pregnancy Outcomes in Women With Type 1 Diabetes

et al. 2021

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“…Khan et al measured FPG and serum fructosamine in 165 pregnant women, 71 and found that FPG and fructosamine could identify high-risk individuals to be screened with the OGTT avoiding unnecessary glucose challenges. At variance with these findings, Li et al measured fructosamine in 161 pregnant women, 72 and reported that this biomarker may be useful for identifying patients at higher risk of abnormal glucose tolerance, but could not be used to predict gestational diabetes mellitus in early pregnancy due to the poor correlations with the outcome of the OGTT.…”

Section: Glycated Albumin and Fructosamine In Gestational Diabetes Mementioning

confidence: 99%

Advantages and Pitfalls of Fructosamine and Glycated Albumin in the Diagnosis and Treatment of Diabetes

Danese

Montagnana

Nouvenne

et al. 2015

J Diabetes Sci Technol

162

139

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Diabetes is one of the most severe and frequent human disorders. According to recent statistics, this condition afflicts as many as 382 million persons around the globe, with an estimated prevalence of approximately 8.3% in 2013. At variance with other frequent pathologies such as cardiovascular disease and bacterial infections, the trend toward an increased prevalence is not expected to soon reverse. Worldwide, as many as 592 million individuals may be affected by diabetes in 2035, a remarkable 55% increase in prevalence over the next 2 decades. 1 Due to its high global prevalence and severe, frequently life-threatening complications (eg, retinopathy, nephropathy, neuropathy, cardiovascular disease), diabetes must be regarded as a serious and increasing global health burden. The most recent Standards of Medical Care in Diabetes published by the American Diabetes Association (ADA) emphasize that early diagnosis and monitoring are critical for preventing or delaying the onset of acute complications and lowering the risk of long-term complications of diabetes. 2 The current diagnostic criteria for this condition are based on the presence of (1) glycated hemoglobin (HbA1c) value ≥6.5% (ie, ≥48 mmol/mol), (2) fasting plasma glucose (FPG) ≥126 mg/dL (ie, ≥7.0 mmol/L), (3) 2-hour plasma glucose ≥200 mg/dL (ie, ≥11.1 mmol/L) during an oral glucose tolerance test (OGTT) using a 75 g glucose load, or (4) random plasma glucose ≥200 mg/dL (ie, ≥11.1 mmol/L). An increased risk of diabetes (ie, prediabetes) is defined in the presence of (1) HbA1c value between 5.7-6.4% (ie, 39-46 mmol/mol), (2) FPG between 100-126 mg/dL (ie, 5.6-6.9 mmol/L), (3) 2-hour plasma glucose between 140-199 mg/ dL (ie, 7.8-11.0 mmol/L) during an OGTT. With regard to diabetes monitoring, the glycemic targets for nonpregnant adults with diabetes include HbA1c value <7.0% (ie, <53 mmol/mol), preprandial capillary plasma glucose between 567227D STXXX10.

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Value of fructosamine measurement in pregnant women with abnormal glucose tolerance

Cited by 18 publications

References 17 publications

Review of methods for detecting glycemic disorders

Review of methods for detecting glycemic disorders

Novel Biochemical Markers of Glycemia to Predict Pregnancy Outcomes in Women With Type 1 Diabetes

Advantages and Pitfalls of Fructosamine and Glycated Albumin in the Diagnosis and Treatment of Diabetes

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