Value of dynamic contrast enhanced magnetic resonance imaging in the differentiation between post-treatment changes and recurrent salivary gland tumors

Samir, Sieza; EL-Adalany, Mohamed Ali; Hamed, Emad

doi:10.1016/j.ejrnm.2016.01.005

Cited by 5 publications

(3 citation statements)

References 24 publications

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“…Radiation therapy is an established modality for treatment of head and neck cancers. 1,2 However, it is known to cause salivary glands impairment resulting in dysfunction and xerostomia. 1 Salivary glands impairment can be reduced through use of modern radiation techniques such as the three dimensional conformal radiation and the intense modulated therapy (IMRT).…”

Section: Introductionmentioning

confidence: 99%

“…1,2 However, it is known to cause salivary glands impairment resulting in dysfunction and xerostomia. 1 Salivary glands impairment can be reduced through use of modern radiation techniques such as the three dimensional conformal radiation and the intense modulated therapy (IMRT). 2,3 However, it is not always economically feasible for all patients to be treated using the modern techniques owing to their economic status hence the use of techniques that do not spare radiation intensity on the healthy tissue in the head and neck region.…”

Section: Introductionmentioning

confidence: 99%

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Imaging salivary glands post external radiation beam therapy of head and neck tumours

Nyathi¹

2018

AMJ

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REVIEWPlease cite this paper as: Nyathi M. Imaging salivary glands post external radiation beam therapy of head and neck tumours. AMJ 2018;11(6):335-342. ABSTRACT BackgroundRadiation therapy using external radiation beam is an established treatment for head and neck cancers. However, salivary glands are exposed leading to severe impairment of oral health. In order to devise patient care strategies, clinicians can measure the degree of salivary gland impairment using various imaging modalities. AimsThe study aimed determining the best imaging modality for measuring salivary glands impairment post external radiation beam therapy of head and neck tumours. MethodsA systematic literature review, performed using Google and Science Direct.com search engines. Publications in English on salivary gland imaging modalities post external radiation beam therapy of head and neck cancers were selected. Information on advantages and disadvantages of the imaging modalities was documented. ResultsThe study established that the Magnetic Resonance Imaging (MRI), Computer Tomography (CT), Ultra Sound (US) depict structural changes while salivary gland scintigraphy provides functional information. It was also established that the obstruction of the salivary glands can be measured using Magnetic Resonance -Sialography. ConclusionThe salivary gland scintigraphy technique is the most sensitive of all salivary gland imaging modalities with the ability to detect slight parenchymal injuries well before structural changes can be seen using the MRI, CT and US. However, when evaluating the obstruction of the salivary glands ducts, the Magnetic Resonance-Sialography modality offers the best option. What this review adds: What is known about this subject?During external beam radiation therapy of head and neck tumours, salivary glands are impaired leading to oral complications among patients. What new information is offered in this review?Salivary glands scintigraphy detects the slightest changes in the function of the salivary glands well before structural changes can be detected using the MRI, the CT and US. What are the implications for research, policy, or practice?Oncologist and clinicians should subject patients treated for head and neck patients to salivary gland scintigraphy during and post treatment in order to assess salivary glands' damage. Information acquired would help to optimize therapy as well as to come up with individualised patient care strategies that would alleviate suffering arising from [AMJ 2018;11(6):335-342] the side effects of therapy.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Imaging salivary glands post external radiation beam therapy of head and neck tumours

Nyathi¹

2018

AMJ

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“…It also identifies early locoregional recurrence, differentiates metastatic lymph nodes from normal nodesand predicts tumour resistance and also serves as an imaging biomarker for hypoxia [3]. DCE-MRI helps in differentiating recurrent malignant salivary gland tumors from post-treatment changes [4]. BOLD MRI analyses changes in magnetic susceptibility of tissue due to paramagnetic deoxy haemoglobin.…”

Section: Introductionmentioning

confidence: 99%