Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging

Ibrahim, El Sayed H.; Frank, Luba; Baruah, Dhiraj; Arpinar, Volkan Emre; Nencka, Andrew S.; Koch, Kevin M.; Muftuler, L. Tugan; Ünal, Orhan; Stojanovska, Jadranka; Rubenstein, Jason; Brown, Sherry‐Ann; Charlson, John; Gore, Elizabeth; Bergom, Carmen

doi:10.1155/2021/8851958

Cited by 10 publications

(11 citation statements)

References 41 publications

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“… 10 , 11 , 139 , 140 , 141 , 142 , 143 , 144 , 146 ; this approach would be quite costly and increase the likelihood of false positive. 165 , 177 Rather, a screening approach guided by cardiac symptoms (e.g. chest pain) and/or triad testing to indicate cMRI will increase its diagnostic yield and feasibility.…”

Section: Discussionmentioning

confidence: 99%

The Impact of COVID-19 on the Cardiovascular Health of Emerging Adults Aged 18-25: Findings From a Scoping Review

Rezler

Ko²,

Jin³

et al. 2023

CJC Pediatric and Congenital Heart Disease

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Section: Discussionmentioning

confidence: 99%

The Impact of COVID-19 on the Cardiovascular Health of Emerging Adults Aged 18-25: Findings From a Scoping Review

Rezler

Ko²,

Jin³

et al. 2023

CJC Pediatric and Congenital Heart Disease

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“…CMR diagnosis also helps with the appropriate management of a patient to optimize the timing of treatment to prevent further complications. Accurate and rapid CMR scans in cancer patients and survivors who have received cancer therapeutics could be beneficial as cancer therapies could lead to cardiomyopathies, myocarditis, or other cardiotoxic effects and heart failure [ 15 ]. A rapid CMR scan could lead to early detection of toxicity and prevention of these treatment complications [ 15 ].…”

Section: Cost Analysis Modelsmentioning

confidence: 99%

“…Accurate and rapid CMR scans in cancer patients and survivors who have received cancer therapeutics could be beneficial as cancer therapies could lead to cardiomyopathies, myocarditis, or other cardiotoxic effects and heart failure [ 15 ]. A rapid CMR scan could lead to early detection of toxicity and prevention of these treatment complications [ 15 ]. Similarly, CMR has become an invaluable tool for the early detection of transplant rejection among patients with cardiac transplants [ 39 ].…”

Section: Cost Analysis Modelsmentioning

confidence: 99%

“…Many myocardial processes that involve microscopic or non-vascular macroscopic fibrosis can readily be detected by CMR as compared to ECHO, which has limited utility in evaluating scar tissue [ 11 , 12 ]. CMR is also the modality of choice in assessments of many non-ischemic pathologies including non-ischemic cardiomyopathies, myocarditis, myocardial tumors, pericardial diseases, cardiotoxicity, inflammatory conditions, valve abnormalities, infiltrative conditions, cardiac masses, and other genetic, metabolic, or idiopathic cardiomyopathies [ 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

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The Merits, Limitations, and Future Directions of Cost-Effectiveness Analysis in Cardiac MRI with a Focus on Coronary Artery Disease: A Literature Review

Siddiqui

Chamarti

Tou

et al. 2022

JCDD

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Cardiac magnetic resonance (CMR) imaging has a wide range of clinical applications with a high degree of accuracy for many myocardial pathologies. Recent literature has shown great utility of CMR in diagnosing many diseases, often changing the course of treatment. Despite this, it is often underutilized possibly due to perceived costs, limiting patient factors and comfort, and longer examination periods compared to other imaging modalities. In this regard, we conducted a literature review using keywords “Cost-Effectiveness” and “Cardiac MRI” and selected articles from the PubMed MEDLINE database that met our inclusion and exclusion criteria to examine the cost-effectiveness of CMR. Our search result yielded 17 articles included in our review. We found that CMR can be cost-effective in quality-adjusted life years (QALYs) in select patient populations with various cardiac pathologies. Specifically, the use of CMR in coronary artery disease (CAD) patients with a pretest probability below a certain threshold may be more cost-effective compared to patients with a higher pretest probability, although its use can be limited based on geographic location, professional society guidelines, and differing reimbursement patterns. In addition, a stepwise combination of different imaging modalities, with conjunction of AHA/ACC guidelines can further enhance the cost-effectiveness of CMR.

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“…Cinematic (CINE) CMR is used to assess the condition and function of the heart in patients with various cardiac diseases and is included by default in virtually any CMR imaging examination [39], [81]. The CINE technique is unique in that it allows clinicians to assess the functionality of the heart by acquiring "movies" demonstrating the heart's motion.…”

Section: Cinematic Cardiac Magnetic Resonancementioning

confidence: 99%

Image Processing Techniques for Analysis of Myocardial Fibrosis and Related Cardiomyopathies in Cardiac Magnetic Resonance Imaging

Farrag¹

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Myocardial fibrosis (MF) is a common feature of cardiac disease, characterized by excessive deposition of collagen (i.e., scar tissue) and expansion of the myocardial extracellular volume (ECV). This phenomenon contributes to cardiac dysfunction, promotes further cardiac disease, and has implication in preceding cardiac morbidity and mortality. The extent of myocardial MF can be analyzed globally (across the entire myocardial region) and/or regionally (across the fibrotic area exclusively) using cardiac magnetic resonance (CMR) imaging techniques, such as late gadolinium enhanced imaging or quantitative methods like native T1 and ECV mapping. CMR-based measurements of MF, native T1, and ECV allow for differentiation between various cardiac disease states and are shown to be clinically significant predictors of patient outcomes. However, in order to analyze tissue volumes or classify disease states, clinicians must first perform a manual tracing of the myocardial borders to define an initial region of interest (ROI), while regional MF quantification requires additional manual selection of a reference healthy myocardial tissue region. These manual processes are tedious, user-dependent, and highly prone to operator error, which can significantly confound resultant measures of T1, ECV and quantified MF tissue zones. Thus, alternative, minimally user-dependent techniques for MF, T1 and ECV quantification are appropriate. In this dissertation, several techniques for improving automated quantification of myocardial T1, ECV, and MF regions are presented. The proposed approaches presented in this document incorporate concepts from deep learning and image processing to achieve automated or semi-automated segmentation of the myocardium, MF, T1 and/or ECV in the left ventricle (LV) and left atrium (LA). experiments, statistical analysis, analyzed results, performed manual segmentations, and wrote the manuscript. S. Bhagavan contributed to algorithm development and performed experiments, evaluated algorithms, and implemented comparisons across various hyperparameters. D. Sebben and S. Ruwanpura completed manual segmentations. J. A.White provided CMR imaging data and contributed to clinical analysis ideas. E. Ukwatta contributed to algorithm development, segmentation evaluation, statistical analysis, and analysis of results. All authors helped in writing the manuscript.Chapter 5 presents materials from the publication in PLOS One entitled "Assessment of left atrial fibrosis progression in canines following rapid ventricular pacing using 3D late gadolinium enhanced CMR images", by N. A.

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Value CMR: Towards a Comprehensive, Rapid, Cost-Effective Cardiovascular Magnetic Resonance Imaging

Cited by 10 publications

References 41 publications

The Impact of COVID-19 on the Cardiovascular Health of Emerging Adults Aged 18-25: Findings From a Scoping Review

The Impact of COVID-19 on the Cardiovascular Health of Emerging Adults Aged 18-25: Findings From a Scoping Review

The Merits, Limitations, and Future Directions of Cost-Effectiveness Analysis in Cardiac MRI with a Focus on Coronary Artery Disease: A Literature Review

Image Processing Techniques for Analysis of Myocardial Fibrosis and Related Cardiomyopathies in Cardiac Magnetic Resonance Imaging

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