Valorization of raw glycerol and crustacean waste into value added products by Yarrowia lipolytica

Magdouli, Sara; Guedri, Tayssir; Rouissi, Tarek; Brar, Satinder Kaur; Blais, Jean-François

doi:10.1016/j.biortech.2017.06.074

Cited by 44 publications

(21 citation statements)

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“…The annual production of biodiesel reaches 41 million tons and elevates annually by 4.5%. Each ton of produced biodiesel gives rise to 100 kg of biodiesel-derived waste glycerol, which poses the problem of its utilization [19,20]. The main disadvantage of the biodiesel-derived waste glycerol application as a carbon substrate is associated with variations in its composition depending on the biodiesel production process and feedstock used.…”

Section: Introductionmentioning

confidence: 99%

Microbiological Production of Isocitric Acid from Biodiesel Waste and Its Effect on Spatial Memory

et al. 2020

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Within this work, the microbial synthesis of (2R,3S)-isocitric acid (ICA), a metabolite of the nonconventional yeast Yarrowia lipolytica, from biodiesel waste, has been studied. The selected strain Y. lipolytica VKM Y-2373 synthesized ICA with citric acid (CA) as a byproduct. This process can be regulated by changing cultivation conditions. The maximal production of ICA with the minimal formation of the byproduct was provided by the use of a concentration of (NH4)2SO4 (6 g/L); the addition of biodiesel waste to cultivation medium in 20–60 g/L portions; maintaining the pH of the cultivation medium at 6, and degree of aeration between 25% and 60% of saturation. Itaconic acid at a concentration of 15 mM favorably influenced the production of ICA by the selected strain. The optimization of cultivation conditions allowed us to increase the concentration of ICA in the culture liquid from 58.32 to 90.2 g/L, the product yield (Y) by 40%, and the ICA/CA ratio from 1.1:1 to 3:1. Research on laboratory animals indicated that ICA counteracted the negative effect of ammonium molybdate (10−5 М) and lead diacetate (10−7 М) on the learning and spatial memory of rats, including those exposed to emotional stress.

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Section: Introductionmentioning

confidence: 99%

Microbiological Production of Isocitric Acid from Biodiesel Waste and Its Effect on Spatial Memory

et al. 2020

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“…6 It is also easy to culture with a short doubling time. Additionally, Y. lipolytica is well characterized especially for lipid and lipase production, 7,8 and has been shown to be amicable to genetic modication, opening up a wide repertoire of possible applications. 9 Several studies have looked into bulk industrial products such as biodiesel and citric acid as possible products of Y. lipolytica.…”

Section: Introductionmentioning

confidence: 99%

Valorization of papaya fruit waste through low-cost fractionation and microbial conversion of both juice and seed lipids

Han

Park

2018

RSC Adv.

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“…Біосинтез інших мікробних метаболітів на змішаних субстратах. Стратегія використання суміші субстратів використовується не лише для отримання ПАР, а й для інших практично цінних мікробних метаболітів: ліпідів [16][17][18][19][20][21][22][23][24], екзополісахаридів [25][26][27], пілігідроксиалканоатів [28][29][30], ферментів [31][32][33], органічних кислот [34][35][36][37][38], пропандіолу [39,40], біоетанолу [41], біоводню [42,43].…”

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“…У [32] досліджували синтез ліпази штамом Yarrowia lipolytica SM7 на суміші технічного гліцерину (40 г/л) з оливковою та соєвою олією (5% мас). Як зазначають автори, додавання олійних субстратів дало змогу зняти репресію синтезу ліпази гліцерином та інтенсифікувати її утворення.…”

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“…Автори праці [32] повідомляють про синтез штамом Y. lipolytica SM7 лимонної кислоти на суміші технічного гліцерину (40 г/л) з оливковою, соєвою олією та моторним мастилом (5% мас.). Встановлено, що використання суміші технічного гліцерину з оливковою та соєвою олією збільшувало концентрацію цитрату на 41 та 90% відповідно.…”

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Intensification of Synthesis of Practically Important Microbial Metabolites on Substrates Mixture

Пирог¹,

Gershtman²,

Penchuk³

2018

SWNUFT

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Mixture of growth substrates Increasing the efficiency of microbial technology Cultivation of microorganisms on mixture of growth substrates allows to avoid unproductive loss of carbon and energy that occurs when using monosubstrates, and also to improve efficiency of transformation of carbon substrates into biomass and to intensify synthesis of secondary metabolites. The paper analyzes the modern scientific literature of last two or five years concerning the increase of synthesis on the mixed substrates (including industrial waste) of primary (organic acids, lipids, enzymes), secondary (polyhydroxyalkanoates, polysaccharides, surface-active substances) metabolites, and also bioethanol and biohydrogen. Using mixture of substrates in microbial technologies enables to increase the rates of synthesis of practically valuable metabolites by 1.5-10 times compared with cultivation producers on corresponding monosubstrates, and in some cases even regulate the composition and properties of final product. Own experimental data on synthesis intensification on mixture of industrial waste (frying sunflower oil, waste of biodiesel production, molasses) of microbial exopolysaccharide ethapolan (producer Acinetobacter sp. IMV B-7005) and Nocardia vaccinii IMV B-7405 surfactants are presented. Unlike most scientists who empirically establish both the concentration of substrates in the mixture and the choice of monosubstrates, in our studies to increase the carbon transformation of substrates mixture into final product, the molar ratio of monosubstrate concentrations in mixture was established on the basis of theoretical calculations of the energy requirement for process biosynthesis. In addition, using mixture of waste to obtain microbial surfactants will not only reduce cost of final product, but also utilize toxic industrial waste and increase profitability of biodiesel production.

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Valorization of raw glycerol and crustacean waste into value added products by Yarrowia lipolytica

Cited by 44 publications

References 46 publications

Microbiological Production of Isocitric Acid from Biodiesel Waste and Its Effect on Spatial Memory

Microbiological Production of Isocitric Acid from Biodiesel Waste and Its Effect on Spatial Memory

Valorization of papaya fruit waste through low-cost fractionation and microbial conversion of both juice and seed lipids

Intensification of Synthesis of Practically Important Microbial Metabolites on Substrates Mixture

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