The physical, chemical, physicochemical and organic characteristics of the soil have a decisive influence on the efficiency of fertilizers, and also on the fertility of the soil and, consequently, on the productivity of the planted crop. This study aimed to evaluate the influence of different doses of organomineral fertilizer on the grain sorghum BRS 330 in Neosol Quartzarênico under no-tillage/SPD system. The work was developed in the experimental area of the Center for Teaching and Research in Phytotechnics, Mineiros, State of Goiás, in the 2017 agricultural year. The treatments consisted of T1: zero Kg ha-1; T2: 150 kg ha-1 (A.O.M.); T3: 300 kg ha-1(A.O.M.); T4: 450 kg ha-1(A.O.M.); T5: 600 kg ha-1; T6: 750 kg ha-1(A.O.M.); T7: 900 Kg ha-1(A.O.M.) Plant height, plant population, weight of a thousand grains and productivity in bags per hectare were evaluated. The experimental design was in randomized blocks, 7x1 scheme with four replications, the data were analyzed by the Assistat program and submitted to analysis of variance, and the means were compared by the t test. We can conclude that the organomineral fertilizer used directly influenced the productivity of grain sorghum BRS 330 implanted in Neosol Quartzarênico.