Validity of the Oxygen Uptake Efficiency Slope in Children With Cystic Fibrosis and Mild-To-Moderate Airflow Obstruction

Bongers, Bart C.; Hulzebos, Erik H.J.; Arets, B.; Takken, Tim

doi:10.1123/pes.24.1.129

Cited by 26 publications

(51 citation statements)

References 37 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…37 Bongers et al's clinical assessment in 2011 obtained the correlation of OUES and VO 2max after being normalized by BSA in healthy children at R = 0.78 and in children with cystic fibrosis patient at R = 0.54. 38 In this context, Akkerman et al 14 in 2010 indicated that in the review of the scientific literature, a high correlation between OUES and VO 2max after being normalized by BSA and LBM can be seen, which are consistent with the results obtained in Iranian adolescent boys. Drinkard et al's study on 12---17 year-old children in 2008 on the impact of body form, revealed that OUES is lower in obese children than non-obese children.…”

Section: Discussionsupporting

confidence: 79%

The role of biological maturation intervention and anthropometric factors on cardiac reserve index (OUES) in Iranian teenage boys

Nazem

Sazvar

2015

Apunts. Medicina de l'Esport

View full text Add to dashboard Cite

The development and organism change, especially changes in biological maturation process, is impressive on the physiological parameters in response to exercise. Hence, the new index oxygen uptake efficiency slope (OUES) role with biological maturity intervention and anthropometric factors of body weight, BSA and LBM which can measure the cardiorespiratory function in children maturity level normal and abnormal (early or late) with high health and safety is important. 72 healthy young males, with a mean age 13.95 ± 1.8 years and BMI 19.91 ± 3.4 kg/m 2 were separated into two groups of normal puberty (n = 33) and abnormal maturation (n = 39). After consent obtaining, their VO 2max was determined by maximal aerobic test via gas analyzer (VE, VO 2 and VCO 2 ). The new index OUES was also determined according to logarithmic relationship Baba. A high correlation was observed between VO 2max and OUES physiological index (R 2 = 0.90, SEE = 292). There was no significant difference in the index OUES with and without the intervention of weight, BSA and LBM between normal and abnormal maturation of boys (p > 0.05). Significant correlation between VO 2max and normalized OUES with anthropometric variables was obtained (R = 0.83, R = 0.87, R = 0.91, p = 0.00). OUES is influenced by weight, BSA and LBM. But the BSA role in the index of cardiac performance was more sensitive than the other two parameters. It appears that due to the lack of intervention maturation effect on this index, during the study of cardiorespiratory system physiological responses of children to exercise, regardless of the maturity the application of this index is possible. © 2015 Consell Català de l'Esport. Document downloaded from http://www.apunts.org, day 24/12/2015. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited. Document downloaded from http://www.apunts.org, day 13/01/2016. This copy is for personal use. Any transmission of this document by any media or format is strictly prohibited. 140 F. Nazem, A. Sazvar PALABRAS CLAVEMadurez; Antropometría; Gradiente de eficiencia de la captación de oxígeno (Oxygen Uptake Efficiency Slope (OUES)) Papel de los factores de maduración biológica y antropométricos en la tasa de reserva cardiaca (TRC) en adolescentes iraníesResumen Los cambios en el desarrollo, especialmente los cambios en el proceso de maduración biológica, pueden conllevar unas diferencias impresionantes en cuanto a los parámetros fisiológicos como respuesta al ejercicio. Por tanto, es importante el papel que representa el nuevo índice del gradiente de eficiencia del consumo de oxígeno (''oxygen uptake efficiency slope (OUES)'' porque incluye variables de maduración biológica, así como factores como el peso corporal antropométrico, el área de la superficie corporal (ASC) y la magra masa corporal (MMC). Por tanto, dicho índice puede medir, de modo seguro, la función cardiorespiratoria en niños con niveles de madurez normal o anormal (temprana o tardía), y aportar una información...

show abstract

Section: Discussionsupporting

confidence: 79%

The role of biological maturation intervention and anthropometric factors on cardiac reserve index (OUES) in Iranian teenage boys

Nazem

Sazvar

2015

Apunts. Medicina de l'Esport

View full text Add to dashboard Cite

show abstract

“…For example, Bongers et al ,29 in a group of 22 children with CF, found Vo 2peak to be significantly lower than healthy controls and Saynor et al 30 found a reduced aerobic capacity (mean Vo 2peak 36.3 mL/kg/min) in those with CF compared with controls.…”

Section: Discussionmentioning

confidence: 98%

Cardiopulmonary exercise testing in children with cystic fibrosis: one centre's experience

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Consideration of altered ventilatory equivalents for CO 2 has featured in heart failure CPET over recent years, however less so in CF, but the reduced elimination of carbon dioxide as a central mechanism may also reduce aerobic fitness. However, use of the OUES and VO 2 gain have been advocated and reported [30,45], but their reliability and validity are still being debated [44]. From a practical point of view, outcome measures which can assess patients' function at submaximal intensities, similar to activities of daily living, are also important.…”

Section: Parameters Of Aerobic Functionmentioning

confidence: 99%

“…The OUES is useful since it is, theoretically, resistant to early test termination and intra-and inter-observer variability [43]. Although these parameters possess documented utility to identify the presence and severity of ventilatory inefficiency of the heart/lung organs and/or response to intervention in heart failure patients, their uptake within the assessment of respiratory conditions has been scarce [44].…”

Section: Parameters Of Aerobic Functionmentioning

confidence: 99%

Cystic fibrosis and physiological responses to exercise

Williams

Saynor

Tomlinson

et al. 2014

Expert Review of Respiratory Medicine

View full text Add to dashboard Cite

Cardiopulmonary exercise testing is underutilized within the clinical management of patients with cystic fibrosis. But within the last 5 years, there has been considerable interest in its implementation, which has included deliberations by the European Cystic Fibrosis Society about incorporating this method within the clinical assessment of patients. This review examines the current use of cardiopulmonary exercise testing in assessing the extent and cause(s) of exercise limitation from a pediatric perspective. Examples of the measured parameters and their interpretation are provided. Critical synthesis of recent work in the oxygen uptake (VO2) kinetics response to and following exercise is also discussed, and although identified more as a research tool, its utilization advances researchers understanding of the cardiovascular, respiratory and muscular limitations to exercise tolerance. Finally, exercise and its application in therapeutic interventions are highlighted and a number of recommendations made about the utility of exercise prescription.

show abstract

Validity of the Oxygen Uptake Efficiency Slope in Children With Cystic Fibrosis and Mild-To-Moderate Airflow Obstruction

Abstract: The OUES is not a valid submaximal measure of cardiopulmonary exercise capacity in children with mild to moderate CF, due to its limited distinguishing properties, its nonlinearity throughout progressive exercise, and its moderate correlation with VO(2peak) and the ventilatory threshold.

Cited by 26 publications

References 37 publications

The role of biological maturation intervention and anthropometric factors on cardiac reserve index (OUES) in Iranian teenage boys

The role of biological maturation intervention and anthropometric factors on cardiac reserve index (OUES) in Iranian teenage boys

Cardiopulmonary exercise testing in children with cystic fibrosis: one centre's experience

Cystic fibrosis and physiological responses to exercise

Contact Info

Product

Resources

About