Validity of echocardiographic determination of left ventricular systolic wall thickening.

Automatic Quantification of Left Ventricular Systolic Wall Thickening Using Two-Dimensional Strain Assessed by a Novel Tissue-Tracking System

“…Quantification of regional wall function had been the subject of many studies within the last two decades. Manually calculated systolic WT reported for the first time by Feneley et al [4]. The %WT had been reported as a reliable and useful index in various clinical practices that may be obtained by either 2-D or M-mode echo [13,14].…”

“…Maximum wall thickness at systole and minimum thickness at diastole were measured using measurement tools of the echo machine. The %WT was calculated as: (maximum thickness -minimum thickness) X 100% / minimum thickness [4,10,11]. Correlation and agreement analysis.…”

“…Percent of systolic wall thickening (%WT) had been introduced and widely used as a quantitative index to assess the left ventricle (LV) regional wall function [4][5][6]. Currently myocardial strain has been introduced as an emerging quantitative index in echocardiography.…”

Improvement in left ventricular function assessed by tissue Doppler imaging after aortic valve replacement for severe aortic stenosis

“…TDI has been shown to be useful in detecting subtle alterations in myocardial function (6) and evaluating regional systolic LV contraction. (9)(10)(11) The use of TDI may be better than conventional measurements which rely on endocardial movement and wall thickening. (9,10) Furthermore, in conventional echocardiographic assessments, global LV diastolic function can only be indirectly derived from the parameters of LV filling.…”

Quantitative analysis of segmental wall motion during maximal upright dynamic exercise: variability in normal adults.

“…Consequently, pathologic significance has been assigned to reduced endocardial segmental motion, especially if it occurs with stress such as exercise.2-7 For example, the development of "hypokinesis" during exercise is widely used as a radionuclide angiographic marker of the presence of significant coronary artery disease.6 7 16 Similarly, "hypokinesis" on left ventricular cineangiograms is frequently used to assess the functional significance of coronary artery stenoses.25-21 However, a number of studies have shown that considerable variability in regional left ventricular endocardial motion occurs in normal individuals. [8][9][10][11][12][13][14][15][16][17][18][19][20][21] Although some of the variability in normal segmental wall motion may be related to technical limitations of the experimental or diagnostic methods used, there is a substantial body of evidence to indicate that at least some of the variability represents true biologic variation. With the use of implanted sonomicrometers in normal dogs, apical segments have been demonstrated to have longer resting fiber lengths and greater magnitudes of systolic shortening than basilar segments.25…”