Validity of Cat and MMRC – Dyspnea Score in Evaluation of Copd Severity

Milacic, Nena; Milacic, Bojan; Dunjić, Olivera; Milojkovic, Maja

doi:10.5633/amm.2015.0111

Cited by 10 publications

(7 citation statements)

References 16 publications

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“…Additionally, the IG had significantly better performances on the mMRC than the CG. The mMRC is moderately correlated with the functional assessments of patients' cardiopulmonary fitness, including FEV1, being therefore an indirect indicator of the respiratory function [25]. Considering the results of the study by Liu et al [16], that conducted a randomized controlled trial to investigate the effects of 6week respiratory rehabilitation training in elderly patients with COVID-19, in which the intervention group had a significantly better respiratory function (evaluated using FEV1), and the results from our study, the mMRC might be considered a good indicator of the improvement in the respiratory function.…”

Section: Discussionmentioning

confidence: 99%

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Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial

Carvalho

Moreira²,

Cubelo³

et al. 2022

ERJ Open Res

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The coronavirus disease 2019 (COVID-19) has led to an increasing number of patients in the intensive care units (ICU). The size of this post-ICU cohort will be unprecedented, with many patients vulnerable to post-intensive care syndrome. We analysed the respiratory and functional effects of a multidisciplinary rehabilitation program on functional performance, in patients hospitalized in ICU due to COVID-19.We conducted a randomized controlled clinical trial. Ninety-six patients, who fulfilled the eligible criteria, were randomized into control or intervention group. The control group received standard of care in the ICU, and the intervention group received a functional and respiratory rehabilitation protocol, that included medical, nursing, physiotherapy, and occupational therapy interventions.At discharge, the intervention group showed significantly better muscular strength and respiratory capacity, and significantly less days of hospitalization (12.90±5.8versus15.60±6.7 days, p=0.037). At the 4- and 12-week follow-up we applied our main outcome measure – 6-minute walking test. The intervention group had significantly better results than the control group on the 6-minute walking test at the 4-week follow-up (604±67versus571±57 m, p=0.018) and at the 12-week follow-up (639±53 37versus611±67, p=0.025).These results support the role of a multidisciplinary rehabilitation program in COVID-19 patients hospitalized in ICU and adds evidence that the implementation of rehabilitation programs in ICU could result in beneficial outcomes for the critical ill patients.

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Section: Discussionmentioning

confidence: 99%

“…At discharge, Medical Research Council dyspnea scale (mMRC) was evaluated. mMRC summarizes the score of five offered statements about breath possibility during the daily activities [25].…”

Section: Assessmentmentioning

confidence: 99%

Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial

Carvalho

Moreira²,

Cubelo³

et al. 2022

ERJ Open Res

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“…The modified Medical Research Council dyspnea scale rates dyspnea intensity on a score between 0 (unimpaired) and 4 (severe) in terms of breathing possibility during daily activities. 27 This dyspnea scale and the BDI/TDI explore dyspnea intensity differently; hence, they complement each other perfectly. 28 …”

Section: Methodsmentioning

confidence: 96%

Adjunctive Inspiratory Muscle Training During a Rehabilitation Program in Patients With Breast Cancer: An Exploratory Double-Blind, Randomized, Controlled Pilot Study

Dahhak

Devoogdt

Langer

2022

Archives of Rehabilitation Research and Clinical Translation

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“…• All patients were asked about their occupational history, smoking history and index [7], comorbidity, number of exacerbations in the last year and their degree, and history of hospital admission in the last year • Complete clinical examination, including Modified Medical Research Council (mMRC) scale of dyspnea [8], peak expiratory flow rate, and oxygen saturation by pulse oximetry • Laboratory investigation including complete blood count (CBC) with differential count (eosinophilic count), liver function test (SGOT and SGPT), kidney function test (urea and creatinine), and sodium and potassium levels • Sputum and blood cytology: The sputum sample was collected at the time of presentation and after treatment, and the differential cell count was evaluated as Hastie et al methods, 2017; hence, the patients were considered to be eosinophilic if the sputum level exceeds 2% and there blood eosinophilia of 0.3 × 10 9 cells/L or greater [9].…”

Section: Patient's Evaluationmentioning

confidence: 99%

Blood and sputum eosinophilia in COPD exacerbation

Helala

AbdelFattah

Elsalam³

2022

Egypt J Bronchol

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Background Exacerbations in chronic obstructive pulmonary disease (COPD) are major contributors to worsening lung function, impaired quality of life, emergency healthcare use, and COPD-related mortality. COPD exacerbations are heterogeneous in terms of airway inflammation and etiology. Objectives To assess the relation between blood and sputum eosinophils and COPD exacerbation. Subjects and methods Prospective cohort study, conducted on 100 COPD patients presented in outpatient clinic. All patients were subjected to medical history including: occupational history, smoking history, comorbidity, number of exacerbations in last year and their degree, history of admission in the last year and treatment taken for COPD. Modified Medical Research Council scale of dyspnea, peak expiratory flow rate, oxygen saturation using pulse oximetry. Complete blood count with differential eosinophilic count. Sputum sample differential cell count was done. Results The eosinophil level in blood before and after treatment showed a significant positive correlation with the number of hospital admission in the last year (r = 0.29; P = 0.003 and r = 0.3; P = 0.002, respectively). Regarding the eosinophil level either in blood or in sputum, it showed significant statistical elevation in patients not using steroid treatment in comparison to patients who used systemic or inhaled steroid treatments (P < 0.001 and 0.004, respectively). Conclusion Blood eosinophil count can be used as a severity marker of COPD exacerbations. The eosinophil levels, either in blood or sputum, were significantly correlated with the degree of exacerbation. Sputum eosinophilia can also predict the risk of hospitalization. In addition, blood eosinophil count can direct the use of oral corticosteroids in exacerbation.

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Validity of Cat and MMRC – Dyspnea Score in Evaluation of Copd Severity

Cited by 10 publications

References 16 publications

Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial

Multidisciplinary rehabilitation in intensive care for COVID-19: randomised controlled trial

Adjunctive Inspiratory Muscle Training During a Rehabilitation Program in Patients With Breast Cancer: An Exploratory Double-Blind, Randomized, Controlled Pilot Study

Blood and sputum eosinophilia in COPD exacerbation

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