Validity of body impedance analysis for evaluating body composition in patients undergoing long-term hemodialysis

Abstract

[Purpose] This study assessed changes in body composition before and after dialysis in chronic hemodialysis patients and determined the relationships between various body composition parameters and blood lipid levels in these patients. [Subjects] The cross-sectional study included 19 dialysis outpatients (17 men and 2 women, aged 35–82 years). [Methods] Body mass index, body weight, percent body fat, and percent skeletal muscle were measured before and after dialysis by using body impedance analysis. Blood lipid levels were obtained from patients’ clinical records. The body composition parameters before and after dialysis were compared using paired t-tests. Spearman’s rank correlation coefficients were calculated to determine relationships between the body composition parameters, before and after dialysis, and the blood lipid levels. [Results] All body composition parameters differed significantly before and after dialysis. High-density lipoprotein cholesterol level significantly correlated with all the body composition parameters, whereas total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels significantly correlated with some of these parameters. The correlation coefficients revealed no major differences in the relationships between blood lipid parameters and body compositions before and after dialysis. [Conclusion] Our findings suggest that body composition parameters, whether measured before or after dialysis, can be used to evaluate obesity in longitudinal studies.

Comparison of Body Composition Monitor and InBody 720 Bioimpedance Devices for Body Composition Estimation in Hemodialysis Patients and Healthy Controls

“…The body composition of hemodialysis (HD) patients undergoes several changes as a result of multiple comorbid conditions, metabolic acidosis, chronic inflammation and the dialysis procedure itself [2,3]. These changes include loss of lean tissue mass [4], changes in body water content and changes in body fat mass [5]. There is an inverse relationship between body cell mass and overhydration in dialysis patients [6].…”

“…There is an inverse relationship between body cell mass and overhydration in dialysis patients [6]. The amount of body water changes significantly before and during each hemodialysis session [5]. Fatty and lean tissue contents are strong and independent predictors of the outcome in dialysis patients and can influence the survival time [7][8][9].…”

“…In today's market, we find numerous methods for estimating body composition, including dual-energy X-ray absorptiometry, computed tomography, magnetic resonance imaging, underwater weighing and body impedance analysis [5]. Devices using the bioelectric impedance method (BIA) are constantly being expanded due to their portability, non-invasiveness and availability [12].…”

“…Devices using the bioelectric impedance method (BIA) are constantly being expanded due to their portability, non-invasiveness and availability [12]. Currently, they are widely used for body composition assessment [13] and allow body composition to be measured without the help of a medical specialist [5]. In BIA, a low electric current is introduced into the body, with lean tissue with a high water content offering low resistance, while fatty tissue with a low water content offers high resistance [5].…”

A systematic review of sleep disorders in patients with chronic kidney disease undergoing hemodialysis

“…The high prevalence (50%) of SDB in patients undergoing hemodialysis (HD) can be attributed to compromised upper airway stability (extracellular fluid volume overload) 21 , 22 , 23 ) , ventilatory control instability (altered central and peripheral chemosensitivity), and reduced upper airway muscle tone (uremia) 24 , 25 , 26 , 27 , 28 ) . Risk factors of SDB in the general population, such as older age, male gender, obesity, smoking, increased neck circumference, and diabetes, are also prevalent in the CKD population 29 ) .…”