Validity and utility of the current definition of binge eating

Wolfe, Barbara E.; Baker, Christina Wood; Smith, Adrian T.; Kelly‐Weeder, Susan

doi:10.1002/eat.20728

Cited by 205 publications

(189 citation statements)

References 119 publications

Supporting

Mentioning

172

Contrasting

Unclassified

Order By: Relevance

“…Of course, human binge eating episodes are a much more complex behavior affecting people for long periods of time (Wolfe et al, 2009). Still, the study of rodent models in a short term fashion can be useful to get insights into some of the neuronal circuits recruited under particular conditions, as it has been previously done in the drugs of abuse research field (Goeders et al, 2009;Steketee and Kalivas, 2011).…”

Section: Discussionmentioning

confidence: 99%

Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling

Valdivia¹,

Cornejo²,

Reynaldo³

et al. 2015

Psychoneuroendocrinology

View full text Add to dashboard Cite

Please cite this article in press as: Valdivia, S., et al., Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling. Psychoneuroendocrinology (2015) and time-limited exposed to a high-fat diet (HFD) display robust binge eating events that gradually escalate over the initial accesses. Intake escalation is proposed to be part of the transition from a controlled to a compulsive or loss of control behavior. Here, we used a combination of behavioral and neuroanatomical studies in mice daily and time-limited exposed to HFD to determine the neuronal brain targets that are activated -as indicated by the marker of cellular activation c-Fos -under these circumstances. Also, we used pharmacologically or genetically manipulated mice to study the role of orexin or ghrelin signaling, respectively, in the modulation of this behavior. We found that four daily and time-limited accesses to HFD induce: (i) a robust hyperphagia with an escalating profile, (ii) an activation of different sub-populations of the ventral tegmental area dopamine neurons and accumbens neurons that is, in general, more pronounced than the activation observed after a single HFD consumption event, and (iii) an activation of the hypothalamic orexin neurons, although orexin signaling blockage fails to affect escalation of HFD intake. In addition, we found that ghrelin receptor-deficient mice fail to both escalate the HFD consumption over the successive days of exposure and fully induce activation of the mesolimbic pathway in response to HFD consumption. Current data suggest that the escalation in high fat intake during repeated accesses differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling.

show abstract

Section: Discussionmentioning

confidence: 99%

Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling

Valdivia¹,

Cornejo²,

Reynaldo³

et al. 2015

Psychoneuroendocrinology

View full text Add to dashboard Cite

show abstract

“…eating and general psychopathology, and also complement accumulating evidence that binge size may be less salient to pathology than loss of control in defining binge eating. [6][7][8]10 AN had the lowest BMI and BN had the highest BMI of the groups. Previous research has generally shown a positive association between OBEs and BMI, 7,16,49 likely attributable to higher caloric intake and retention from overeating episodes.…”

Section: Descriptive Statisticsmentioning

confidence: 91%

“…[6][7][8] Accumulating evidence suggests that the perception of loss of control over eating, regardless of the amount of food consumed, is the critical feature of binge episodes, [8][9][10] and studies related to binge eating have highlighted that size is not always relevant to the perception of a binge eating episode. Women from the community who self-identified binge eating episodes, placed more importance on the loss of control dimension, and classified nearly one-half of subjective bulimic episodes as eating binges, even though intake was not objectively large.…”

Section: Introductionmentioning

confidence: 99%

“…11 Food diaries from patients with BN have shown ''binges'' of \100 kcal and that a third classify episodes involving \500 kcal as binges. 8 Regressions predicting pathology from objective binge episodes (OBEs) and subjective binge episodes (SBEs) in BN have shown that the difference in type of eating binge does not account for variance in eating pathology, psychiatric symptoms, or Axis I and II comorbidity, indicating that the eating episodes could not be differentiated. 10,12 The labeling of an eating episode as a binge, rather than objective caloric intake, appears to be more predictive of purging among women with BN.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Subjective binge eating with compensatory behaviors: A variant presentation of bulimia nervosa

Watson

Fursland

Bulik

2012

Intl J Eating Disorders

View full text Add to dashboard Cite

Objectives: To determine whether a variant bulimic-type presentation, whereby one meets criteria for bulimia nervosa (BN) except that binge eating episodes are not objectively large (i.e., ''subjective bulimia nervosa,'' SBN), has comparable clinical severity to established eating disorders, particularly BN.Method: Treatment-seeking adults with BN (N 5 112), SBN (N 5 28), anorexia nervosa restricting type (AN-R) (N 5 45), and AN-binge/purge type (AN-B/P) (N 5 24) were compared.Results: Overall, SBN could not be meaningfully distinguished from BN. SBN and BN had equivalent eating pathology, depression and anxiety symptoms, low quality of life, impulsivity, Axis I comorbidity, and lifetime psychiatric history, and comparable clinical severity to AN-R and AN-B/P. Discussion: Individuals with SBN, differing from BN only by the smaller size of their binge eating episodes, had a form of eating disorder comparable in clinical severity to threshold AN and BN and warranting clinical attention. Health professionals and the community require greater awareness of this variant to optimize detection, treatment-seeking, and outcomes. V V C 2012 by Wiley Periodicals, Inc.

show abstract

“…Studies with non-clinical samples have reported a wide variation in the prevalence of binge eating, which seems to be directly related to the definition used for classifying the outcome (6) . Those evaluating recurrent binge eating have found lower prevalence rates than those who considered one or more episodes of binge eating (7)(8)(9)(10)(11) .…”

mentioning

confidence: 99%

Binge eating in adults: prevalence and association with obesity, poor self-rated health status and body dissatisfaction

França

Gigante

Olinto

2013

Public Health Nutr.

View full text Add to dashboard Cite

Objective: To estimate the prevalence of episodes of binge eating and to assess potential associations with nutritional status, satisfaction with current body weight, self-rated health status and self-rated body weight. Design: A cross-sectional population-based study. Binge eating was assessed using adapted questions from the Brazilian Portuguese version of the Questionnaire on Eating and Weight Patterns and was defined as binging one or more times over the last 3 months before the interview. Setting: City of Pelotas, southern Brazil. Subjects: Individuals (n 2097) aged 20-59 years. Results: The prevalence of binge eating and recurrent binge eating was 7?9 % and 2?7 %, respectively. In the adjusted analysis, obesity, fair/poor self-rated health status and body dissatisfaction remained strongly associated with binge eating. Conclusions: The study showed a high prevalence of binge eating among adults in Pelotas, being higher among younger women, the obese and those who desired to weigh less. The current results are informative, but longitudinal studies would be needed to demonstrate the causal relationship between these events.

show abstract

Validity and utility of the current definition of binge eating

Cited by 205 publications

References 119 publications

Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling

Escalation in high fat intake in a binge eating model differentially engages dopamine neurons of the ventral tegmental area and requires ghrelin signaling

Subjective binge eating with compensatory behaviors: A variant presentation of bulimia nervosa

Binge eating in adults: prevalence and association with obesity, poor self-rated health status and body dissatisfaction

Contact Info

Product

Resources

About